TY - JOUR
T1 - Interobserver variability of colposcopic, interpretations and consistency with final histologic results
AU - Sideri, Mario
AU - Spolti, Noemi
AU - Spinaci, Laura
AU - Sanvito, Francesca
AU - Ribaldone, Raffaella
AU - Surico, Nicola
AU - Bucchi, Lauro
PY - 2004/7
Y1 - 2004/7
N2 - Objective. To evaluate the interobserver reliability of colposcopy and the prediction of final histologic results. Materials and Methods. Visibility of the squamocolumnar junction, presence and grading of atypical transformation zone (ATZ), and presence and grading of cervical intraepithelial neoplasia (CIN) were assessed by nine expert colposcopists in 100 cervigrams, Pairwise κ, group κ, and class-specific κ values were computed. Frequency and degree of interobserver disagreement on CIN and ATZ grading and correlation with histologic results were studied. Results. The median pairwise κ and the group κ values were excellent for ATZ detection, acceptable for the squamocolumnar junction, and poor for the other variables; the presence of ATZ had a sensitivity for CIN of 90.2% and a specificity of 48.6%; the colposcopic impression of high-grade CIN had a sensitivity of 54.4% and a specificity of 88%. Conclusions. Some colposcopic predictions are reproduc-ible between observers, predictive of the histologic results, and can be integrated in the algorithm for the management of patients with abnormal Pap smear results.
AB - Objective. To evaluate the interobserver reliability of colposcopy and the prediction of final histologic results. Materials and Methods. Visibility of the squamocolumnar junction, presence and grading of atypical transformation zone (ATZ), and presence and grading of cervical intraepithelial neoplasia (CIN) were assessed by nine expert colposcopists in 100 cervigrams, Pairwise κ, group κ, and class-specific κ values were computed. Frequency and degree of interobserver disagreement on CIN and ATZ grading and correlation with histologic results were studied. Results. The median pairwise κ and the group κ values were excellent for ATZ detection, acceptable for the squamocolumnar junction, and poor for the other variables; the presence of ATZ had a sensitivity for CIN of 90.2% and a specificity of 48.6%; the colposcopic impression of high-grade CIN had a sensitivity of 54.4% and a specificity of 88%. Conclusions. Some colposcopic predictions are reproduc-ible between observers, predictive of the histologic results, and can be integrated in the algorithm for the management of patients with abnormal Pap smear results.
KW - Colposcopy
KW - Histology
KW - Variability
UR - http://www.scopus.com/inward/record.url?scp=3042857724&partnerID=8YFLogxK
U2 - 10.1097/00128360-200407000-00009
DO - 10.1097/00128360-200407000-00009
M3 - Article
SN - 1089-2591
VL - 8
SP - 212
EP - 216
JO - Journal of Lower Genital Tract Disease
JF - Journal of Lower Genital Tract Disease
IS - 3
ER -