Interobserver variability of colposcopic, interpretations and consistency with final histologic results

Mario Sideri, Noemi Spolti, Laura Spinaci, Francesca Sanvito, Raffaella Ribaldone, Nicola Surico, Lauro Bucchi

Risultato della ricerca: Contributo su rivistaArticolo in rivistapeer review

Abstract

Objective. To evaluate the interobserver reliability of colposcopy and the prediction of final histologic results. Materials and Methods. Visibility of the squamocolumnar junction, presence and grading of atypical transformation zone (ATZ), and presence and grading of cervical intraepithelial neoplasia (CIN) were assessed by nine expert colposcopists in 100 cervigrams, Pairwise κ, group κ, and class-specific κ values were computed. Frequency and degree of interobserver disagreement on CIN and ATZ grading and correlation with histologic results were studied. Results. The median pairwise κ and the group κ values were excellent for ATZ detection, acceptable for the squamocolumnar junction, and poor for the other variables; the presence of ATZ had a sensitivity for CIN of 90.2% and a specificity of 48.6%; the colposcopic impression of high-grade CIN had a sensitivity of 54.4% and a specificity of 88%. Conclusions. Some colposcopic predictions are reproduc-ible between observers, predictive of the histologic results, and can be integrated in the algorithm for the management of patients with abnormal Pap smear results.

Lingua originaleInglese
pagine (da-a)212-216
Numero di pagine5
RivistaJournal of Lower Genital Tract Disease
Volume8
Numero di pubblicazione3
DOI
Stato di pubblicazionePubblicato - lug 2004
Pubblicato esternamente

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