Interferon signature in immunosuppressed patients with lower respiratory tract infections: dosage on bronchoalveolar lavage

Interferon signature (IS) is the measure of transcripts belonging to pathways of interferon activation. Viral infections can interfere with the interferon pathway, in particular herpesvirus present in immunocompromised hosts. The aim of our study was to evaluate if herpesvirus infections in immunocompromised patients with lower tract respiratory infections (LTRI) could lead to IS alterations.