Interaction of dipyridamole with phospholipid monolayers at the air-water interface: Surface pressure and grazing incidence X-ray diffraction studies

H. Haas; W. Caetano; G. P. Borissevitch; M. Tabak; M. I. Mosquera Sanchez; O. N. Oliveira; Enrico Scalas; Michel Goldmann

doi:10.1016/S0009-2614(00)01464-0

Interaction of dipyridamole with phospholipid monolayers at the air-water interface: Surface pressure and grazing incidence X-ray diffraction studies

H. Haas, W. Caetano, G. P. Borissevitch, M. Tabak, M. I. Mosquera Sanchez, O. N. Oliveira, Enrico Scalas, Michel Goldmann

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

Incorporation of dipyridamole (DIP) in Langmuir monolayers of the zwitterionic phospholipid dipalmitoylphosphatidylcholine (DPPC) has been investigated using surface pressure isotherm and grazing incidence X-ray diffraction (GIXD) measurements. An expansion in the pressure-area isotherms of the DPPC monolayer was observed, which was maximum in the liquid-expanded (LE) to liquid-condensed (LC) transition region and at a DIP concentration of 2 mol%. Accordingly, the GIXD measurements indicated an expansion of the 2D lattice in the LC phase up to a surface pressure of ca. 30 mN/m. A condensation effect on the DPPC packing for high DIP concentrations, as previously suggested, can be ruled out.

Lingua originale	Inglese
pagine (da-a)	510-516
Numero di pagine	7
Rivista	Chemical Physics Letters
Volume	335
Numero di pubblicazione	5-6
DOI	https://doi.org/10.1016/S0009-2614(00)01464-0
Stato di pubblicazione	Pubblicato - 2 mar 2001
Pubblicato esternamente	Sì

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10.1016/S0009-2614(00)01464-0

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Haas, H., Caetano, W., Borissevitch, G. P., Tabak, M., Mosquera Sanchez, M. I., Oliveira, O. N., Scalas, E., & Goldmann, M. (2001). Interaction of dipyridamole with phospholipid monolayers at the air-water interface: Surface pressure and grazing incidence X-ray diffraction studies. Chemical Physics Letters, 335(5-6), 510-516. https://doi.org/10.1016/S0009-2614(00)01464-0

@article{7b7d972e69c14f44b0d861de7df4427c,

title = "Interaction of dipyridamole with phospholipid monolayers at the air-water interface: Surface pressure and grazing incidence X-ray diffraction studies",

abstract = "Incorporation of dipyridamole (DIP) in Langmuir monolayers of the zwitterionic phospholipid dipalmitoylphosphatidylcholine (DPPC) has been investigated using surface pressure isotherm and grazing incidence X-ray diffraction (GIXD) measurements. An expansion in the pressure-area isotherms of the DPPC monolayer was observed, which was maximum in the liquid-expanded (LE) to liquid-condensed (LC) transition region and at a DIP concentration of 2 mol%. Accordingly, the GIXD measurements indicated an expansion of the 2D lattice in the LC phase up to a surface pressure of ca. 30 mN/m. A condensation effect on the DPPC packing for high DIP concentrations, as previously suggested, can be ruled out.",

author = "H. Haas and W. Caetano and Borissevitch, {G. P.} and M. Tabak and {Mosquera Sanchez}, {M. I.} and Oliveira, {O. N.} and Enrico Scalas and Michel Goldmann",

note = "Funding Information: This work was supported by EU TMR (HH, ES) (project number DF803-98) and the Brazilian agencies FAPESP, CNPq and FINEP. We are grateful to the LURE, France, for the beamtime allocation at beamline D41-B and for generous financial and technical support.",

year = "2001",

month = mar,

day = "2",

doi = "10.1016/S0009-2614(00)01464-0",

language = "English",

volume = "335",

pages = "510--516",

journal = "Chemical Physics Letters",

issn = "0009-2614",

publisher = "Elsevier B.V.",

number = "5-6",

}

Haas, H, Caetano, W, Borissevitch, GP, Tabak, M, Mosquera Sanchez, MI, Oliveira, ON, Scalas, E & Goldmann, M 2001, 'Interaction of dipyridamole with phospholipid monolayers at the air-water interface: Surface pressure and grazing incidence X-ray diffraction studies', Chemical Physics Letters, vol. 335, n. 5-6, pagg. 510-516. https://doi.org/10.1016/S0009-2614(00)01464-0

TY - JOUR

T1 - Interaction of dipyridamole with phospholipid monolayers at the air-water interface

T2 - Surface pressure and grazing incidence X-ray diffraction studies

AU - Haas, H.

AU - Caetano, W.

AU - Borissevitch, G. P.

AU - Tabak, M.

AU - Mosquera Sanchez, M. I.

AU - Oliveira, O. N.

AU - Scalas, Enrico

AU - Goldmann, Michel

N1 - Funding Information: This work was supported by EU TMR (HH, ES) (project number DF803-98) and the Brazilian agencies FAPESP, CNPq and FINEP. We are grateful to the LURE, France, for the beamtime allocation at beamline D41-B and for generous financial and technical support.

PY - 2001/3/2

Y1 - 2001/3/2

N2 - Incorporation of dipyridamole (DIP) in Langmuir monolayers of the zwitterionic phospholipid dipalmitoylphosphatidylcholine (DPPC) has been investigated using surface pressure isotherm and grazing incidence X-ray diffraction (GIXD) measurements. An expansion in the pressure-area isotherms of the DPPC monolayer was observed, which was maximum in the liquid-expanded (LE) to liquid-condensed (LC) transition region and at a DIP concentration of 2 mol%. Accordingly, the GIXD measurements indicated an expansion of the 2D lattice in the LC phase up to a surface pressure of ca. 30 mN/m. A condensation effect on the DPPC packing for high DIP concentrations, as previously suggested, can be ruled out.

AB - Incorporation of dipyridamole (DIP) in Langmuir monolayers of the zwitterionic phospholipid dipalmitoylphosphatidylcholine (DPPC) has been investigated using surface pressure isotherm and grazing incidence X-ray diffraction (GIXD) measurements. An expansion in the pressure-area isotherms of the DPPC monolayer was observed, which was maximum in the liquid-expanded (LE) to liquid-condensed (LC) transition region and at a DIP concentration of 2 mol%. Accordingly, the GIXD measurements indicated an expansion of the 2D lattice in the LC phase up to a surface pressure of ca. 30 mN/m. A condensation effect on the DPPC packing for high DIP concentrations, as previously suggested, can be ruled out.

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U2 - 10.1016/S0009-2614(00)01464-0

DO - 10.1016/S0009-2614(00)01464-0

M3 - Article

SN - 0009-2614

VL - 335

SP - 510

EP - 516

JO - Chemical Physics Letters

JF - Chemical Physics Letters

IS - 5-6

ER -

Interaction of dipyridamole with phospholipid monolayers at the air-water interface: Surface pressure and grazing incidence X-ray diffraction studies

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