Intensive insulin therapy in preschool-aged diabetic children: From multiple daily injections to continuous subcutaneous insulin infusion through indwelling catheters

Ivana Rabbone, A. Bobbio, V. di Gianni, C. Sacchetti, F. Cerutti

Risultato della ricerca: Contributo su rivistaArticolo in rivistapeer review

Abstract

In this study, glycemic control, diabetes care indices and quality of life (QoL) were assessed in 2 groups of newly diagnosed Type I diabetic subjects <6 yr old who were randomized to multiple daily injections with (Group A) or without (Group B) an indwelling catheter. Group A [12 males (M)/8 females (F), mean age 3.2±1.4 yr] and Group B (9M/I I F, mean age 3.9±1.8 yr) were evaluated at baseline and after 6 and 12 months of treatment. No significant difference was observed in metabolic control (glycosylated hemoglobin) or in the number of hypoglycemic events between the groups. Patients in Group A had a greater number of daily insulin injections, monitored blood glucose more frequently and had a lower total daily insulin dose per kg (p<0.05). QoL was better in group A. At the end of the study 30% of group A patients progressed to continuous sc insulin infusion (CSII), while no child in Group B switched to a different insulin regimen. Based on these findings, indwelling catheter therapy may be helpful for selected CSII candidates.

Lingua originaleInglese
pagine (da-a)193-195
Numero di pagine3
RivistaJournal of Endocrinological Investigation
Volume31
Numero di pubblicazione3
DOI
Stato di pubblicazionePubblicato - mar 2008
Pubblicato esternamente

Fingerprint

Entra nei temi di ricerca di 'Intensive insulin therapy in preschool-aged diabetic children: From multiple daily injections to continuous subcutaneous insulin infusion through indwelling catheters'. Insieme formano una fingerprint unica.

Cita questo