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ICOS deficiency hampers the homeostasis, development and function of NK cells
María Montes-Casado1
, Gloria Ojeda
, Laura Aragoneses-Fenoll
, Daniel López
, Belén De Andrés
, María Luisa Gaspar
,
Umberto Dianzani
, José M. Rojo
, Pilar Portolés
Dipartimento di Scienze della Salute
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Keyphrases
Homeostasis
100%
Natural Killer Cells
100%
ICOS Deficiency
100%
Interleukin-2
28%
ICOS Ligand
28%
Altered Expression
14%
Cell number
14%
KO Mice
14%
Cytotoxicity
14%
Cell Activity
14%
Cell Differentiation
14%
NK Cell Activity
14%
Inducible Costimulator
14%
Germinal Center
14%
Intracellular Signaling
14%
Clinical Phenotype
14%
Akt Phosphorylation
14%
Innate Immune Response
14%
Cellular Homeostasis
14%
Cell-mediated
14%
CD11b
14%
Effector Function
14%
Intrinsic Defects
14%
Novel Therapeutic Targets
14%
Virus Infection
14%
Bone Marrow chimera
14%
CD27
14%
NK1.1
14%
Delayed Maturation
14%
Vaccinia Virus
14%
Cell-intrinsic
14%
Immune Parameters
14%
Poly IC
14%
Cell Defects
14%
ICOSL
14%
Bone Marrow-derived Dendritic Cells
14%
Innate Cells
14%
Functional Importance
14%
CD122
14%
NK Cell Markers
14%
Chimera Mice
14%
Activated NK Cells
14%
C Virus
14%
Immunology and Microbiology
Homeostasis
100%
Natural Killer Cell
100%
Interleukin 2
20%
Inducible T Cell Costimulator Ligand
20%
Innate Immune System
10%
Viral Disease
10%
Secretion (Process)
10%
Maturation
10%
Polyinosinic:polycytidylic Acid
10%
Cytotoxicity
10%
Germinal Center
10%
Immunocompetent Cell
10%
Intracellular Signaling
10%
Knockout Mouse
10%
Cell Activation
10%
Cell Population
10%
Vaccinia Virus
10%
Cell Marker
10%
Bone Marrow Derived Dendritic Cell
10%