TY - JOUR
T1 - Hypofractionation for postoperative breast cancer radiotherapy
T2 - Is acute toxicity a limiting factor?
AU - Krengli, Marco
AU - Terrazzino, Salvatore
AU - Deantonio, Letizia
PY - 2016
Y1 - 2016
N2 - Whole-breast radiotherapy (RT) after conservative surgery in women with early breast cancer is the standard of care, providing a reduction of local recurrence and breast cancer mortality (1). In order to facilitate the access to RT centers, to optimize the allocation of RT resources, and to preserve the patient quality of life, the scientific community has investigated the efficacy and toxicity of abbreviated courses of postoperative breast RT by using a radiobiologically-equivalent total dose with hypofractionated schedules in randomized controlled trials as well as in several prospective and retrospective studies (2-5).
AB - Whole-breast radiotherapy (RT) after conservative surgery in women with early breast cancer is the standard of care, providing a reduction of local recurrence and breast cancer mortality (1). In order to facilitate the access to RT centers, to optimize the allocation of RT resources, and to preserve the patient quality of life, the scientific community has investigated the efficacy and toxicity of abbreviated courses of postoperative breast RT by using a radiobiologically-equivalent total dose with hypofractionated schedules in randomized controlled trials as well as in several prospective and retrospective studies (2-5).
UR - http://www.scopus.com/inward/record.url?scp=84996837303&partnerID=8YFLogxK
U2 - 10.21037/tcr.2016.10.14
DO - 10.21037/tcr.2016.10.14
M3 - Editorial
SN - 2218-676X
VL - 5
SP - S684-S687
JO - Translational Cancer Research
JF - Translational Cancer Research
ER -