Highly enantioselective epoxidation catalyzed by cinchona thioureas: Synthesis of functionalized terminal epoxides bearing a quaternary stereogenic center

Alessio Russo; Gerardina Galdi; Gianluca Croce; Alessandra Lattanzi

doi:10.1002/chem.201200500

Highly enantioselective epoxidation catalyzed by cinchona thioureas: Synthesis of functionalized terminal epoxides bearing a quaternary stereogenic center

Alessio Russo, Gerardina Galdi, Gianluca Croce, Alessandra Lattanzi

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

A brilliant debut! Cinchona thioureas have been reported for the first time as catalysts in the area of asymmetric oxidations. They efficiently promote an unprecedented highly enantioselective epoxidation of deactivated 1,1-disubstituted alkenes to terminal epoxides containing a quaternary stereogenic center (see scheme).

Lingua originale	Inglese
pagine (da-a)	6152-6157
Numero di pagine	6
Rivista	Chemistry - A European Journal
Volume	18
Numero di pubblicazione	20
DOI	https://doi.org/10.1002/chem.201200500
Stato di pubblicazione	Pubblicato - 14 mag 2012
Pubblicato esternamente	Sì

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10.1002/chem.201200500

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title = "Highly enantioselective epoxidation catalyzed by cinchona thioureas: Synthesis of functionalized terminal epoxides bearing a quaternary stereogenic center",

abstract = "A brilliant debut! Cinchona thioureas have been reported for the first time as catalysts in the area of asymmetric oxidations. They efficiently promote an unprecedented highly enantioselective epoxidation of deactivated 1,1-disubstituted alkenes to terminal epoxides containing a quaternary stereogenic center (see scheme).",

keywords = "alkenes, asymmetric synthesis, cinchona thioureas, epoxides, organocatalysis",

author = "Alessio Russo and Gerardina Galdi and Gianluca Croce and Alessandra Lattanzi",

year = "2012",

month = may,

day = "14",

doi = "10.1002/chem.201200500",

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journal = "Chemistry - A European Journal",

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Highly enantioselective epoxidation catalyzed by cinchona thioureas: Synthesis of functionalized terminal epoxides bearing a quaternary stereogenic center. / Russo, Alessio; Galdi, Gerardina; Croce, Gianluca et al.
In: Chemistry - A European Journal, Vol. 18, N. 20, 14.05.2012, pag. 6152-6157.

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

TY - JOUR

T1 - Highly enantioselective epoxidation catalyzed by cinchona thioureas

T2 - Synthesis of functionalized terminal epoxides bearing a quaternary stereogenic center

AU - Russo, Alessio

AU - Galdi, Gerardina

AU - Croce, Gianluca

AU - Lattanzi, Alessandra

PY - 2012/5/14

Y1 - 2012/5/14

N2 - A brilliant debut! Cinchona thioureas have been reported for the first time as catalysts in the area of asymmetric oxidations. They efficiently promote an unprecedented highly enantioselective epoxidation of deactivated 1,1-disubstituted alkenes to terminal epoxides containing a quaternary stereogenic center (see scheme).

AB - A brilliant debut! Cinchona thioureas have been reported for the first time as catalysts in the area of asymmetric oxidations. They efficiently promote an unprecedented highly enantioselective epoxidation of deactivated 1,1-disubstituted alkenes to terminal epoxides containing a quaternary stereogenic center (see scheme).

KW - alkenes

KW - asymmetric synthesis

KW - cinchona thioureas

KW - epoxides

KW - organocatalysis

UR - https://www.scopus.com/pages/publications/84860702714

U2 - 10.1002/chem.201200500

DO - 10.1002/chem.201200500

M3 - Article

SN - 0947-6539

VL - 18

SP - 6152

EP - 6157

JO - Chemistry - A European Journal

JF - Chemistry - A European Journal

IS - 20

ER -

Highly enantioselective epoxidation catalyzed by cinchona thioureas: Synthesis of functionalized terminal epoxides bearing a quaternary stereogenic center

Abstract

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