High doses of onabotulinumtoxinA in post-stroke spasticity: a retrospective analysis

Alessio Baricich; Elisa Grana; Stefano Carda; Andrea Santamato; Carlo Cisari; Marco Invernizzi

doi:10.1007/s00702-015-1384-6

High doses of onabotulinumtoxinA in post-stroke spasticity: a retrospective analysis

Alessio Baricich
, Elisa Grana
, Stefano Carda
, Andrea Santamato
, Carlo Cisari
, Marco Invernizzi

Dipartimento di Scienze della Salute

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

We retrospectively evaluated the efficacy and safety of high doses of onabotulinumtoxinA (from 600 to 800 units) in 26 patients affected by upper and/or lower limb post-stroke spasticity. They were assessed before, 30 and 90 days after treatment. We observed a significant muscle tone reduction and a significant functional improvement (assessed with the Disability Assessment Scale). No adverse events were reported. In our retrospective analysis the treatment with high doses of onabotulinumtoxinA showed to be effective and safe.

Lingua originale	Inglese
pagine (da-a)	1283-1287
Numero di pagine	5
Rivista	Journal of Neural Transmission
Volume	122
Numero di pubblicazione	9
DOI	https://doi.org/10.1007/s00702-015-1384-6
Stato di pubblicazione	Pubblicato - 21 set 2015

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title = "High doses of onabotulinumtoxinA in post-stroke spasticity: a retrospective analysis",

abstract = "We retrospectively evaluated the efficacy and safety of high doses of onabotulinumtoxinA (from 600 to 800 units) in 26 patients affected by upper and/or lower limb post-stroke spasticity. They were assessed before, 30 and 90 days after treatment. We observed a significant muscle tone reduction and a significant functional improvement (assessed with the Disability Assessment Scale). No adverse events were reported. In our retrospective analysis the treatment with high doses of onabotulinumtoxinA showed to be effective and safe.",

keywords = "Botulinum toxin type A, Higher doses, OnabotulinumtoxinA, Spasticity, Stroke",

author = "Alessio Baricich and Elisa Grana and Stefano Carda and Andrea Santamato and Carlo Cisari and Marco Invernizzi",

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T2 - a retrospective analysis

AU - Baricich, Alessio

AU - Grana, Elisa

AU - Carda, Stefano

AU - Santamato, Andrea

AU - Cisari, Carlo

AU - Invernizzi, Marco

PY - 2015/9/21

Y1 - 2015/9/21

N2 - We retrospectively evaluated the efficacy and safety of high doses of onabotulinumtoxinA (from 600 to 800 units) in 26 patients affected by upper and/or lower limb post-stroke spasticity. They were assessed before, 30 and 90 days after treatment. We observed a significant muscle tone reduction and a significant functional improvement (assessed with the Disability Assessment Scale). No adverse events were reported. In our retrospective analysis the treatment with high doses of onabotulinumtoxinA showed to be effective and safe.

AB - We retrospectively evaluated the efficacy and safety of high doses of onabotulinumtoxinA (from 600 to 800 units) in 26 patients affected by upper and/or lower limb post-stroke spasticity. They were assessed before, 30 and 90 days after treatment. We observed a significant muscle tone reduction and a significant functional improvement (assessed with the Disability Assessment Scale). No adverse events were reported. In our retrospective analysis the treatment with high doses of onabotulinumtoxinA showed to be effective and safe.

KW - Botulinum toxin type A

KW - Higher doses

KW - OnabotulinumtoxinA

KW - Spasticity

KW - Stroke

UR - https://www.scopus.com/pages/publications/84939573418

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VL - 122

SP - 1283

EP - 1287

JO - Journal of Neural Transmission

JF - Journal of Neural Transmission

IS - 9

ER -

High doses of onabotulinumtoxinA in post-stroke spasticity: a retrospective analysis

Abstract

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