High doses of onabotulinumtoxinA in post-stroke spasticity: a retrospective analysis

Alessio Baricich, Elisa Grana, Stefano Carda, Andrea Santamato, Carlo Cisari, Marco Invernizzi

Risultato della ricerca: Contributo su rivistaArticolo in rivistapeer review

Abstract

We retrospectively evaluated the efficacy and safety of high doses of onabotulinumtoxinA (from 600 to 800 units) in 26 patients affected by upper and/or lower limb post-stroke spasticity. They were assessed before, 30 and 90 days after treatment. We observed a significant muscle tone reduction and a significant functional improvement (assessed with the Disability Assessment Scale). No adverse events were reported. In our retrospective analysis the treatment with high doses of onabotulinumtoxinA showed to be effective and safe.

Lingua originaleInglese
pagine (da-a)1283-1287
Numero di pagine5
RivistaJournal of Neural Transmission
Volume122
Numero di pubblicazione9
DOI
Stato di pubblicazionePubblicato - 21 set 2015

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