Glucose, insulin and renin activity after sodium loading and depletion in Vipera aspis

Maria Angela Masini, Bianca Maria Uva

Risultato della ricerca: Contributo su rivistaArticolo in rivistapeer review

Abstract

Sodium, potassium, chloride, glucose, insulin and renin activity were investigated in fasted Vipera aspis subjected for 3 days to administration of 3% NaCl 5 ml, or injection of a diuretic and water loading to produce sodium depletion. After sodium loading, plasma sodium and glucose were significantly elevated if compared with those of controls, while plasma renin-like activity and plasma insulin were depressed. The insulin and somatostatin producing cells (B- and D-cells) showed only a weak immunoreactivity, while in the glucagon producing cells (A-cells) the immunoreactivity was stronger if compared with the handled controls. After sodium depletion, plasma sodium and glucose were significantly depressed and plasma renin-like activity and plasma insulin were significantly elevated. A strong immunoreactivity was present in B- and D-cells and only a weak immunoreactivity was detectable in the A-cells. These data suggest that the secretory activity of the endocrine pancreas and kidney may be affected, in vipers, by sodium and/or volume status.

Lingua originaleInglese
pagine (da-a)375-380
Numero di pagine6
RivistaComparative Biochemistry and Physiology - C Pharmacology Toxicology and Endocrinology
Volume113
Numero di pubblicazione3
DOI
Stato di pubblicazionePubblicato - mar 1996
Pubblicato esternamente

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