Glucometrics and device satisfaction in children and adolescents with type 1 diabetes using different treatment modalities: A multicenter real-world observational study

Valentino Cherubini, Andrea Fargalli, Claudia Arnaldi, Marta Bassi, Riccardo Bonfanti, Giulia Patrizia Bracciolini, Francesca Cardella, Sara Dal Bo, Maurizio Delvecchio, Francesca Di Candia, Roberto Franceschi, Sabrina Maria Galassi, Francesco Gallo, Vanna Graziani, Antonio Iannilli, Chiara Mameli, Marco Marigliano, Nicola Minuto, Sara Monti, Enza MozzilloFilomena Pascarella, Barbara Predieri, Ivana Rabbone, Rosalia Roppolo, Riccardo Schiaffini, Valentina Tiberi, Davide Tinti, Sonia Toni, Andrea Scaramuzza, Benedetta Vestrucci, Rosaria Gesuita

Risultato della ricerca: Contributo su rivistaArticolo in rivistapeer review

Abstract

Aims: To analyze metabolic outcomes, diabetes impact and device satisfaction in children and adolescents with type 1 diabetes in Italy who used different treatment modalities for diabetes care in a real-life context. Methods: In this multicenter, nationwide, cross-sectional study, 1464 participants were enrolled at a routine visit. The following treatment modalities were considered MDI + SMBG; MDI + CGM; Sensor Augmented Pump Therapy; predictive management of low glucose; Hybrid Closed Loop (HCL); Advanced Hybrid Closed Loop (AHCL). Health related quality of life was evaluated by the Italian version of the Diabetes Impact and Device Satisfaction Scale (DIDS) questionnaire. Results: Patients treated with AID systems were more likely to have HbA1c ≤ 6.5 %, higher percentage of time with glucose levels between 70 and 180 mg/dL, lower percentage of time with glucose levels above 180 mg/dL, higher device satisfaction, and reduced impact of diabetes. All the therapeutic modalities with respect to MDI + CGM, except for MDI + SMBG, contributed to increase the device satisfaction. HCL and AHCL respect to MDI + CGM were associated with lower diabetes impact. Conclusion: Real-life use of automated insulin delivery systems is associated with reduced type 1 diabetes impact, increased device satisfaction, and achievement of glycemic goals.

Lingua originaleInglese
Numero di articolo111621
RivistaDiabetes Research and Clinical Practice
Volume210
DOI
Stato di pubblicazionePubblicato - apr 2024

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