Genetic Polymorphisms Affecting the Pharmacokinetics of Antiretroviral Drugs

Andrea CALCAGNO; JESSICA CUSATO; ANTONIO D'AVOLIO; Stefano BONORA

doi:10.1007/s40262-016-0456-6

Genetic Polymorphisms Affecting the Pharmacokinetics of Antiretroviral Drugs

Andrea CALCAGNO
, JESSICA CUSATO
, ANTONIO D'AVOLIO
, Stefano BONORA

Dipartimento di Medicina Traslazionale

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

Antiretroviral treatment is highly effective in enhancing HIV-positive patients' survival and quality of life. Despite an increased tolerability in recent years, a substantial amount of patients experience side effects. Antiretrovirals' efficacy and tolerability have been associated with plasma concentrations and single nucleotide polymorphisms in selected genes involved in drug disposition.

Lingua originale	Inglese
pagine (da-a)	355-369
Numero di pagine	15
Rivista	Clinical Pharmacokinetics
Volume	56
Numero di pubblicazione	4
DOI	https://doi.org/10.1007/s40262-016-0456-6
Stato di pubblicazione	Pubblicato - 2017

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10.1007/s40262-016-0456-6

https://hdl.handle.net/11579/216836

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abstract = "Antiretroviral treatment is highly effective in enhancing HIV-positive patients' survival and quality of life. Despite an increased tolerability in recent years, a substantial amount of patients experience side effects. Antiretrovirals' efficacy and tolerability have been associated with plasma concentrations and single nucleotide polymorphisms in selected genes involved in drug disposition.",

author = "Andrea CALCAGNO and JESSICA CUSATO and ANTONIO D'AVOLIO and Stefano BONORA",

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AU - BONORA, Stefano

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AB - Antiretroviral treatment is highly effective in enhancing HIV-positive patients' survival and quality of life. Despite an increased tolerability in recent years, a substantial amount of patients experience side effects. Antiretrovirals' efficacy and tolerability have been associated with plasma concentrations and single nucleotide polymorphisms in selected genes involved in drug disposition.

UR - https://iris.uniupo.it/handle/11579/216836

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M3 - Article

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JO - Clinical Pharmacokinetics

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Genetic Polymorphisms Affecting the Pharmacokinetics of Antiretroviral Drugs

Abstract

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