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G protein–coupled receptor 21 in macrophages: An in vitro study
Valentina Bordano
, Gemma K. Kinsella
, Stefania Cannito
, Chiara Dianzani
, Casimiro Luca Gigliotti
, John C. Stephens
, Chiara Monge
, Claudia Bocca
, Arianna C. Rosa
, Gianluca Miglio
,
Umberto Dianzani
, John B.C. Findlay
, Elisa Benetti
Dipartimento di Scienze della Salute
Risultato della ricerca
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Keyphrases
In Vitro Study
100%
Macrophages
100%
G Protein-coupled Receptor
100%
GPR21
100%
GRA2
40%
Cell Migration
30%
Pharmacological Inhibitors
30%
M1 Macrophages
30%
Cytokine Release
20%
M2 Macrophages
20%
THP-1 Cells
20%
Inverse Agonist
20%
G Protein
10%
Signaling Pathway
10%
Cell Viability
10%
Pathological Conditions
10%
Receptor Expression
10%
Protein Level
10%
Small Interfering RNA (siRNA)
10%
Interleukin-1β
10%
Knock-in Mouse Model
10%
Migration Assay
10%
Gene Level
10%
Opposite Effects
10%
Cell Cytokines
10%
Migratory Ability
10%
Human Macrophages
10%
Boyden Chamber
10%
Human Peripheral Blood Monocytes
10%
Low-grade Inflammation
10%
Macrophage Migration
10%
Constitutive Activated Receptor
10%
Immunology and Microbiology
Macrophage
100%
In Vitro
100%
Cell Migration
60%
Agonist
40%
Cytokine Release
40%
M2 Macrophages
40%
Tumor Necrosis Factor
20%
Signal Transduction
20%
Knockout Mouse
20%
Cell Viability
20%
ELISA
20%
Interleukin 1
20%
Macrophage Migration
20%
THP-1 Cell Line
20%
Pharmacology, Toxicology and Pharmaceutical Science
Receptor
100%
Cytokine
66%
Inverse Agonist
66%
Guanine Nucleotide Binding Protein
33%
Tumor Necrosis Factor
33%
Cell Viability
33%
Enzyme-Linked Immunosorbent Assay
33%
Interleukin 1
33%
Knockout Mouse
33%
Small Interfering RNA
33%
Chronic Inflammation
33%
G Protein Coupled Receptor
33%
Biochemistry, Genetics and Molecular Biology
In Vitro Study
100%
Macrophage
100%
Cell Migration
42%
Cytokine Release
28%
Inverse Agonist
28%
Signal Transduction
14%
Knockout Mouse
14%
Cell Viability
14%
Tumor Necrosis Factor
14%
Interleukin-1
14%
G Protein Coupled Receptor
14%
Macrophage Migration
14%
G Protein
14%
Small Interfering RNA
14%