TY - JOUR
T1 - Exploring new roles for case-based reasoning in heterogeneous AI systems for medical decision support
AU - Montani, Stefania
N1 - Funding Information:
We are currently applying TA as a pre-processing step to the End Stage Renal Disease (ESRD) domain, within a project funded by the Italian Ministry of Education (grant PRIN 2004 number 2004094558). ESRD is a severe chronic condition that corresponds to the final stage of kidney failure. Without medical intervention, ESRD leads to death. Haemodialysis is the most widely used treatment method for ESRD; it relies on an electromechanical device, called haemodialyzer, which, thanks to an extra-corporal blood circuit, is able to clear the patient’s blood from catabolites, to re-establish acid-base equilibrium and to remove water in excess. On average, haemodialysis patients are treated for four hours three times a week. Each single treatment is called a haemodialysis session. Haemodialyzers typically allow to collect several variables during a session, most of which are in the form of time series. In our system, time series pre-processed through TA can then be manually analyzed by physicians, or provided as an input to an automatic reasoner (whose description is outside the scope of this paper, see [9]).
PY - 2008/6
Y1 - 2008/6
N2 - Background Supporting medical decision making is a complex task, that offers challenging research issues to Artificial Intelligence (AI) scientists. The Case-based Reasoning (CBR) methodology has been proposed as a possible means for supporting decision making in this domain since the 1980s. Nevertheless, despite the variety of efforts produced by the CBR research community, and the number of issues properly handled by means of this methodology, the success of CBR systems in medicine is somehow limited, and almost no research product has been fully tested and commercialized; one of the main reasons for this may be found in the nature of the problem domain, which is extremely complex and multi-faceted. Materials and methods In this environment, we propose to design a modular architecture, in which several AI methodologies cooperate, to provide decision support. In the resulting context CBR, originally conceived as a well suited reasoning paradigm for medical applications, can extend its original roles, and cover a set of additional tasks. Results and conclusions As an example, in the paper we will show how CBR can be exploited for configuring the parameters relied upon by other (reasoning) modules. Other possible ways of deploying CBR in this domain will be the object of our future investigations, and, in our opinion, a possible research direction for people working on CBR in the health sciences.
AB - Background Supporting medical decision making is a complex task, that offers challenging research issues to Artificial Intelligence (AI) scientists. The Case-based Reasoning (CBR) methodology has been proposed as a possible means for supporting decision making in this domain since the 1980s. Nevertheless, despite the variety of efforts produced by the CBR research community, and the number of issues properly handled by means of this methodology, the success of CBR systems in medicine is somehow limited, and almost no research product has been fully tested and commercialized; one of the main reasons for this may be found in the nature of the problem domain, which is extremely complex and multi-faceted. Materials and methods In this environment, we propose to design a modular architecture, in which several AI methodologies cooperate, to provide decision support. In the resulting context CBR, originally conceived as a well suited reasoning paradigm for medical applications, can extend its original roles, and cover a set of additional tasks. Results and conclusions As an example, in the paper we will show how CBR can be exploited for configuring the parameters relied upon by other (reasoning) modules. Other possible ways of deploying CBR in this domain will be the object of our future investigations, and, in our opinion, a possible research direction for people working on CBR in the health sciences.
UR - http://www.scopus.com/inward/record.url?scp=43449127783&partnerID=8YFLogxK
U2 - 10.1007/s10489-007-0046-2
DO - 10.1007/s10489-007-0046-2
M3 - Article
SN - 0924-669X
VL - 28
SP - 275
EP - 285
JO - Applied Intelligence
JF - Applied Intelligence
IS - 3
ER -