European multi-centre comparison of thallium 201 and technetium 99m methoxyisobutylisonitrile in ischaemic heart disease

M. N. Maisey; A. Lowry; A. Bischof-Delaloye; R. Fridrich; E. Inglese; M. N. Khalil; J. B. van der Schoot

doi:10.1007/BF01280254

European multi-centre comparison of thallium 201 and technetium 99m methoxyisobutylisonitrile in ischaemic heart disease

M. N. Maisey, A. Lowry, A. Bischof-Delaloye, R. Fridrich, E. Inglese, M. N. Khalil, J. B. van der Schoot

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

Fifty-six patients in Europe were entered into a multi-centre study to compare the accuracy of technetium 99m methoxyisobutylisonitrile (^99mTc-MIBI) for the detection of coronary artery disease (CAD) with thallium 201 (²⁰¹T1) chloride perfusion scanning. The results showed a high degree of concordance between the two radiopharmaceuticals. Some 81% (678/840) of myocardial segments showed the same result (normal, infarct or ischaemia), and 80% (45/56) of patients had the same diagnosis. Overall detection of CAD in patients was 98% for²⁰¹T1 and 96% for^99mTc-MIBI. Detection of CAD in total arteries was 68% for both agents. In this study^99mTc-MIBI was as accurate as²⁰¹T1 for the detection of coronary artery stenoses.

Lingua originale	Inglese
pagine (da-a)	869-872
Numero di pagine	4
Rivista	European Journal of Nuclear Medicine
Volume	16
Numero di pubblicazione	12
DOI	https://doi.org/10.1007/BF01280254
Stato di pubblicazione	Pubblicato - dic 1990
Pubblicato esternamente	Sì

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10.1007/BF01280254

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title = "European multi-centre comparison of thallium 201 and technetium 99m methoxyisobutylisonitrile in ischaemic heart disease",

abstract = "Fifty-six patients in Europe were entered into a multi-centre study to compare the accuracy of technetium 99m methoxyisobutylisonitrile (99mTc-MIBI) for the detection of coronary artery disease (CAD) with thallium 201 (201T1) chloride perfusion scanning. The results showed a high degree of concordance between the two radiopharmaceuticals. Some 81% (678/840) of myocardial segments showed the same result (normal, infarct or ischaemia), and 80% (45/56) of patients had the same diagnosis. Overall detection of CAD in patients was 98% for201T1 and 96% for99mTc-MIBI. Detection of CAD in total arteries was 68% for both agents. In this study99mTc-MIBI was as accurate as201T1 for the detection of coronary artery stenoses.",

keywords = "Coronary heart disease, Multi-centre comparison, Myocardial imaging, Technetium 99m methoxyisobutylisonitrile, Thallium 201",

author = "Maisey, {M. N.} and A. Lowry and A. Bischof-Delaloye and R. Fridrich and E. Inglese and Khalil, {M. N.} and {van der Schoot}, {J. B.}",

year = "1990",

month = dec,

doi = "10.1007/BF01280254",

language = "English",

volume = "16",

pages = "869--872",

journal = "European Journal of Nuclear Medicine",

issn = "0340-6997",

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T1 - European multi-centre comparison of thallium 201 and technetium 99m methoxyisobutylisonitrile in ischaemic heart disease

AU - Maisey, M. N.

AU - Lowry, A.

AU - Bischof-Delaloye, A.

AU - Fridrich, R.

AU - Inglese, E.

AU - Khalil, M. N.

AU - van der Schoot, J. B.

PY - 1990/12

Y1 - 1990/12

N2 - Fifty-six patients in Europe were entered into a multi-centre study to compare the accuracy of technetium 99m methoxyisobutylisonitrile (99mTc-MIBI) for the detection of coronary artery disease (CAD) with thallium 201 (201T1) chloride perfusion scanning. The results showed a high degree of concordance between the two radiopharmaceuticals. Some 81% (678/840) of myocardial segments showed the same result (normal, infarct or ischaemia), and 80% (45/56) of patients had the same diagnosis. Overall detection of CAD in patients was 98% for201T1 and 96% for99mTc-MIBI. Detection of CAD in total arteries was 68% for both agents. In this study99mTc-MIBI was as accurate as201T1 for the detection of coronary artery stenoses.

AB - Fifty-six patients in Europe were entered into a multi-centre study to compare the accuracy of technetium 99m methoxyisobutylisonitrile (99mTc-MIBI) for the detection of coronary artery disease (CAD) with thallium 201 (201T1) chloride perfusion scanning. The results showed a high degree of concordance between the two radiopharmaceuticals. Some 81% (678/840) of myocardial segments showed the same result (normal, infarct or ischaemia), and 80% (45/56) of patients had the same diagnosis. Overall detection of CAD in patients was 98% for201T1 and 96% for99mTc-MIBI. Detection of CAD in total arteries was 68% for both agents. In this study99mTc-MIBI was as accurate as201T1 for the detection of coronary artery stenoses.

KW - Coronary heart disease

KW - Multi-centre comparison

KW - Myocardial imaging

KW - Technetium 99m methoxyisobutylisonitrile

KW - Thallium 201

UR - http://www.scopus.com/inward/record.url?scp=0025074203&partnerID=8YFLogxK

U2 - 10.1007/BF01280254

DO - 10.1007/BF01280254

M3 - Article

SN - 0340-6997

VL - 16

SP - 869

EP - 872

JO - European Journal of Nuclear Medicine

JF - European Journal of Nuclear Medicine

IS - 12

ER -

European multi-centre comparison of thallium 201 and technetium 99m methoxyisobutylisonitrile in ischaemic heart disease

Abstract

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