Erratum to: GLP-1: Benefits beyond pancreas

G. Muscogiuri; A. Cignarelli; F. Giorgino; F. Prodam; D. Santi; G. Tirabassi; G. Balercia; R. Modica; A. Faggiano; A. Colao

doi:10.1007/s40618-014-0188-0

Erratum to: GLP-1: Benefits beyond pancreas

G. Muscogiuri, A. Cignarelli, F. Giorgino, F. Prodam, D. Santi, G. Tirabassi, G. Balercia, R. Modica, A. Faggiano, A. Colao

Dipartimento di Scienze della Salute

Risultato della ricerca: Contributo su rivista › Commento

Abstract

Glucagon-like peptide 1 (GLP-1) is an intestinal hormone secreted after the ingestion of various nutrients. The main role of GLP-1 is to stimulate insulin secretion in a glucose-dependent manner. However, the expression of GLP-1 receptor was found to be expressed in a variety of tissues beyond pancreas such as lung, stomach, intestine, kidney, heart and brain. Beyond pancreas, a beneficial effect of GLP-1 on body weight reduction has been shown, suggesting its role for the treatment of obesity. In addition, GLP-1 has been demonstrated to reduce cardiovascular risk factors and to have a direct cardioprotective effect, fostering heart recovery after ischemic injury. Further, data from both experimental animal models and human studies have shown beneficial effect of GLP-1 on bone metabolism, either directly or indirectly on bone cells.

Lingua originale	Inglese
pagine (da-a)	115
Numero di pagine	1
Rivista	Journal of Endocrinological Investigation
Volume	38
Numero di pubblicazione	1
DOI	https://doi.org/10.1007/s40618-014-0188-0
Stato di pubblicazione	Pubblicato - 1 gen 2015

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10.1007/s40618-014-0188-0

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AU - Muscogiuri, G.

AU - Cignarelli, A.

AU - Giorgino, F.

AU - Prodam, F.

AU - Santi, D.

AU - Tirabassi, G.

AU - Balercia, G.

AU - Modica, R.

AU - Faggiano, A.

AU - Colao, A.

PY - 2015/1/1

Y1 - 2015/1/1

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AB - Glucagon-like peptide 1 (GLP-1) is an intestinal hormone secreted after the ingestion of various nutrients. The main role of GLP-1 is to stimulate insulin secretion in a glucose-dependent manner. However, the expression of GLP-1 receptor was found to be expressed in a variety of tissues beyond pancreas such as lung, stomach, intestine, kidney, heart and brain. Beyond pancreas, a beneficial effect of GLP-1 on body weight reduction has been shown, suggesting its role for the treatment of obesity. In addition, GLP-1 has been demonstrated to reduce cardiovascular risk factors and to have a direct cardioprotective effect, fostering heart recovery after ischemic injury. Further, data from both experimental animal models and human studies have shown beneficial effect of GLP-1 on bone metabolism, either directly or indirectly on bone cells.

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SP - 115

JO - Journal of Endocrinological Investigation

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ER -

Erratum to: GLP-1: Benefits beyond pancreas

Abstract

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