Effect of anti μ chain specific immunosuppression on Chikungunya virus encephalitis of mice

M. Giovarelli; I. Viano; M. Zucca; R. Valbonesi; F. Dianzanil

doi:10.1128/iai.16.3.849-852.1977

Effect of anti μ chain specific immunosuppression on Chikungunya virus encephalitis of mice

M. Giovarelli, I. Viano, M. Zucca, R. Valbonesi, F. Dianzanil

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

Mice neonatally immunosuppressed with anti-μ antiserum failed to produce circulating antibodies to sheep erythrocytes and showed a marked decrease in circulating immunoglobulins. However, when they were intracerebrally infected with Chikungunya virus (a group A togavirus), they showed a mortality rate consistently lower than non-immunosuppressed control mice. Several possible explanations for this finding are discussed.

Lingua originale	Inglese
pagine (da-a)	849-852
Numero di pagine	4
Rivista	Unknown Journal
Volume	16
Numero di pubblicazione	3
DOI	https://doi.org/10.1128/iai.16.3.849-852.1977
Stato di pubblicazione	Pubblicato - 1977
Pubblicato esternamente	Sì

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10.1128/iai.16.3.849-852.1977

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title = "Effect of anti μ chain specific immunosuppression on Chikungunya virus encephalitis of mice",

abstract = "Mice neonatally immunosuppressed with anti-μ antiserum failed to produce circulating antibodies to sheep erythrocytes and showed a marked decrease in circulating immunoglobulins. However, when they were intracerebrally infected with Chikungunya virus (a group A togavirus), they showed a mortality rate consistently lower than non-immunosuppressed control mice. Several possible explanations for this finding are discussed.",

author = "M. Giovarelli and I. Viano and M. Zucca and R. Valbonesi and F. Dianzanil",

year = "1977",

doi = "10.1128/iai.16.3.849-852.1977",

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T1 - Effect of anti μ chain specific immunosuppression on Chikungunya virus encephalitis of mice

AU - Giovarelli, M.

AU - Viano, I.

AU - Zucca, M.

AU - Valbonesi, R.

AU - Dianzanil, F.

PY - 1977

Y1 - 1977

N2 - Mice neonatally immunosuppressed with anti-μ antiserum failed to produce circulating antibodies to sheep erythrocytes and showed a marked decrease in circulating immunoglobulins. However, when they were intracerebrally infected with Chikungunya virus (a group A togavirus), they showed a mortality rate consistently lower than non-immunosuppressed control mice. Several possible explanations for this finding are discussed.

AB - Mice neonatally immunosuppressed with anti-μ antiserum failed to produce circulating antibodies to sheep erythrocytes and showed a marked decrease in circulating immunoglobulins. However, when they were intracerebrally infected with Chikungunya virus (a group A togavirus), they showed a mortality rate consistently lower than non-immunosuppressed control mice. Several possible explanations for this finding are discussed.

UR - https://www.scopus.com/pages/publications/0017710101

U2 - 10.1128/iai.16.3.849-852.1977

DO - 10.1128/iai.16.3.849-852.1977

M3 - Article

VL - 16

SP - 849

EP - 852

JO - Unknown Journal

JF - Unknown Journal

IS - 3

ER -

Effect of anti μ chain specific immunosuppression on Chikungunya virus encephalitis of mice

Abstract

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