Dynamic interplay between cell types during wound healing

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Abstract

Wound healing is a complex biological process requiring regulated interactions between cells, local and systemic growth factors and the extracellular matrix components in which these entities interact.Tissue restoration involves several biochemical processes of tissue repair like granular tissue formation, matrix deposition, and re-epithelialization. All these events involve active participation of various cell types and their cross talk plays an important role during the wound healing process.We summarize the interplays between keratinocytes and others cells, such as endothelial cells, fibroblasts and inflammatory cells, and how these cell types impact to control the re-epithelialization, angiogenesis and the extracellular matrix remodeling. The best knowledge of this process will open new therapeutic interventions on skin wounds.

Lingua originaleInglese
Titolo della pubblicazione ospiteKeratinocytes
Sottotitolo della pubblicazione ospiteStructure, Molecular Mechanisms and Role in Immunity
EditoreNova Science Publishers, Inc.
Pagine1-11
Numero di pagine11
ISBN (stampa)9781626187986
Stato di pubblicazionePubblicato - 2013

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