Drosophila vitelline membrane cross-linking requires the fs(1)Nasrat, fs(1)polehole and chorion genes activities

FILIPPO MARIA CERNILOGAR, F. Fabbri, D. Andrenacci, C. Taddei, G. Gargiulo

Risultato della ricerca: Contributo su rivistaArticolo in rivistapeer review

Abstract

During the final step of Drosophila vitelline membrane formation, the structural proteins composing this layer become cross-linked by covalent bonds. In the present report, we analyzed the vitelline membrane cross-linking in mutants having defects either in this layer or in the chorionic layers. In the fs(1)Nasrat and fs(1)polehole mutant alleles conferring defects in vitelline membrane formation, disruption of vitelline membrane cross-linking was observed, indicating the involvement of these two genes in the process. On the contrary, in the fs(1)Nasrat and fs(1)polehole alleles showing defects only at the termini of the embryo the vitelline membrane is properly formed, confirming a multifunctional activity of their gene products. Altered vitelline membrane cross-linking was also detected in a mutant of the chorion protein gene Cp36 and in the chorion amplification mutant fs(1)K1214, suggesting a role of the structural components of chorion layers in the process of vitelline membrane hardening.
Lingua originaleInglese
pagine (da-a)573-580
Numero di pagine8
RivistaDevelopment Genes and Evolution
Volume211
Numero di pubblicazione12
DOI
Stato di pubblicazionePubblicato - 2001

Keywords

  • Chorion genes
  • Eggshell
  • VM26A.2
  • fs(1)Nasrat
  • fs(1)polehole

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