Diterpenoids from Euphorbia pithyusa subsp. cupanii

Giovanni Appendino; Emanuela Belloro; Gian Cesare Tron; Jasmin Jakupovic; Mauro Ballero

doi:10.1021/np990209u

Diterpenoids from Euphorbia pithyusa subsp. cupanii

Giovanni Appendino, Emanuela Belloro, Gian Cesare Tron, Jasmin Jakupovic, Mauro Ballero

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

The aerial parts of Euphorbia pithyusa subsp, cupanii collected in Sardinia afforded eleven novel diterpenoids belonging to the lathyrane (1a), premyrsinane (4a-g), and tigliane (5a-c) types. Compounds 4a-g and 5a are esters of two new parent alcohols, named premyrsinol and 4,12,20- trideoxyphorbol, respectively. Structures were elucidated by spectroscopic and chemical methods. Puzzling differences between the NMR data of lathyrol (1c) and its esters were rationalized in terms of flipping of the exomethylene around the mean plane of the macrocycle.

Lingua originale	Inglese
pagine (da-a)	1399-1404
Numero di pagine	6
Rivista	Journal of Natural Products
Volume	62
Numero di pubblicazione	10
DOI	https://doi.org/10.1021/np990209u
Stato di pubblicazione	Pubblicato - ott 1999
Pubblicato esternamente	Sì

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10.1021/np990209u

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title = "Diterpenoids from Euphorbia pithyusa subsp. cupanii",

abstract = "The aerial parts of Euphorbia pithyusa subsp, cupanii collected in Sardinia afforded eleven novel diterpenoids belonging to the lathyrane (1a), premyrsinane (4a-g), and tigliane (5a-c) types. Compounds 4a-g and 5a are esters of two new parent alcohols, named premyrsinol and 4,12,20- trideoxyphorbol, respectively. Structures were elucidated by spectroscopic and chemical methods. Puzzling differences between the NMR data of lathyrol (1c) and its esters were rationalized in terms of flipping of the exomethylene around the mean plane of the macrocycle.",

author = "Giovanni Appendino and Emanuela Belloro and Tron, {Gian Cesare} and Jasmin Jakupovic and Mauro Ballero",

year = "1999",

month = oct,

doi = "10.1021/np990209u",

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T1 - Diterpenoids from Euphorbia pithyusa subsp. cupanii

AU - Appendino, Giovanni

AU - Belloro, Emanuela

AU - Tron, Gian Cesare

AU - Jakupovic, Jasmin

AU - Ballero, Mauro

PY - 1999/10

Y1 - 1999/10

N2 - The aerial parts of Euphorbia pithyusa subsp, cupanii collected in Sardinia afforded eleven novel diterpenoids belonging to the lathyrane (1a), premyrsinane (4a-g), and tigliane (5a-c) types. Compounds 4a-g and 5a are esters of two new parent alcohols, named premyrsinol and 4,12,20- trideoxyphorbol, respectively. Structures were elucidated by spectroscopic and chemical methods. Puzzling differences between the NMR data of lathyrol (1c) and its esters were rationalized in terms of flipping of the exomethylene around the mean plane of the macrocycle.

AB - The aerial parts of Euphorbia pithyusa subsp, cupanii collected in Sardinia afforded eleven novel diterpenoids belonging to the lathyrane (1a), premyrsinane (4a-g), and tigliane (5a-c) types. Compounds 4a-g and 5a are esters of two new parent alcohols, named premyrsinol and 4,12,20- trideoxyphorbol, respectively. Structures were elucidated by spectroscopic and chemical methods. Puzzling differences between the NMR data of lathyrol (1c) and its esters were rationalized in terms of flipping of the exomethylene around the mean plane of the macrocycle.

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DO - 10.1021/np990209u

M3 - Article

SN - 0163-3864

VL - 62

SP - 1399

EP - 1404

JO - Journal of Natural Products

JF - Journal of Natural Products

IS - 10

ER -

Diterpenoids from Euphorbia pithyusa subsp. cupanii

Abstract

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