Diterpenoids from cascarilla (Croton eluteria Bennet)

Ernesto Fattorusso; Orazio Taglialatela-Scafati; Claudio Campagnuolo; Federico U. Santelia; Giovanni Appendino; Paola Spagliardi

doi:10.1021/jf0203693

Diterpenoids from cascarilla (Croton eluteria Bennet)

Ernesto Fattorusso, Orazio Taglialatela-Scafati, Claudio Campagnuolo, Federico U. Santelia, Giovanni Appendino, Paola Spagliardi

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

Cascarilla is a commercially available and cheap source of polyfunctionalized diterpenoids belonging to the clerodane structural type. In addition to the bitter triol cascarillin, 10 additional new diterpenoids (eluterins A-J) have been isolated and characterized by spectroscopic means. Structural diversity within cascarilla clerodanes involves mainly the linkage between the carbocyclic and the heterocyclic moieties and the functionalization of C-3, C-4, and C-6 of the decalin core. Cascarillin was shown to be a mixture of interconverting γ-lactols and not a γ-hydroxyaldehyde as previously reported.

Lingua originale	Inglese
pagine (da-a)	5131-5138
Numero di pagine	8
Rivista	Journal of Agricultural and Food Chemistry
Volume	50
Numero di pubblicazione	18
DOI	https://doi.org/10.1021/jf0203693
Stato di pubblicazione	Pubblicato - 28 ago 2002
Pubblicato esternamente	Sì

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10.1021/jf0203693

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title = "Diterpenoids from cascarilla (Croton eluteria Bennet)",

abstract = "Cascarilla is a commercially available and cheap source of polyfunctionalized diterpenoids belonging to the clerodane structural type. In addition to the bitter triol cascarillin, 10 additional new diterpenoids (eluterins A-J) have been isolated and characterized by spectroscopic means. Structural diversity within cascarilla clerodanes involves mainly the linkage between the carbocyclic and the heterocyclic moieties and the functionalization of C-3, C-4, and C-6 of the decalin core. Cascarillin was shown to be a mixture of interconverting γ-lactols and not a γ-hydroxyaldehyde as previously reported.",

keywords = "Bitter compounds, Cascarilla, Clerodane, Croton eluteria, Diterpenes, Eluterins, NMR spectroscopy",

author = "Ernesto Fattorusso and Orazio Taglialatela-Scafati and Claudio Campagnuolo and Santelia, \{Federico U.\} and Giovanni Appendino and Paola Spagliardi",

year = "2002",

month = aug,

day = "28",

doi = "10.1021/jf0203693",

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journal = "Journal of Agricultural and Food Chemistry",

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T1 - Diterpenoids from cascarilla (Croton eluteria Bennet)

AU - Fattorusso, Ernesto

AU - Taglialatela-Scafati, Orazio

AU - Campagnuolo, Claudio

AU - Santelia, Federico U.

AU - Appendino, Giovanni

AU - Spagliardi, Paola

PY - 2002/8/28

Y1 - 2002/8/28

N2 - Cascarilla is a commercially available and cheap source of polyfunctionalized diterpenoids belonging to the clerodane structural type. In addition to the bitter triol cascarillin, 10 additional new diterpenoids (eluterins A-J) have been isolated and characterized by spectroscopic means. Structural diversity within cascarilla clerodanes involves mainly the linkage between the carbocyclic and the heterocyclic moieties and the functionalization of C-3, C-4, and C-6 of the decalin core. Cascarillin was shown to be a mixture of interconverting γ-lactols and not a γ-hydroxyaldehyde as previously reported.

AB - Cascarilla is a commercially available and cheap source of polyfunctionalized diterpenoids belonging to the clerodane structural type. In addition to the bitter triol cascarillin, 10 additional new diterpenoids (eluterins A-J) have been isolated and characterized by spectroscopic means. Structural diversity within cascarilla clerodanes involves mainly the linkage between the carbocyclic and the heterocyclic moieties and the functionalization of C-3, C-4, and C-6 of the decalin core. Cascarillin was shown to be a mixture of interconverting γ-lactols and not a γ-hydroxyaldehyde as previously reported.

KW - Bitter compounds

KW - Cascarilla

KW - Clerodane

KW - Croton eluteria

KW - Diterpenes

KW - Eluterins

KW - NMR spectroscopy

UR - https://www.scopus.com/pages/publications/0037189863

U2 - 10.1021/jf0203693

DO - 10.1021/jf0203693

M3 - Article

SN - 0021-8561

VL - 50

SP - 5131

EP - 5138

JO - Journal of Agricultural and Food Chemistry

JF - Journal of Agricultural and Food Chemistry

IS - 18

ER -

Diterpenoids from cascarilla (Croton eluteria Bennet)

Abstract

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