TY - JOUR
T1 - Development of two multiplex PCR systems for the analysis of 12 X-chromosomal STR loci in a northwestern Italian population sample
AU - Robino, C.
AU - Giolitti, A.
AU - Gino, S.
AU - Torre, C.
PY - 2006/9
Y1 - 2006/9
N2 - Two multiplex polymerase chain reaction systems for the automated profiling of 12 X-chromosomal short tandem repeat (STR) markers were developed. Multiplex A consisted of DXS6789, DXS6809, GATA172D05, DXS101, DXS8378, and DXS8377. Multiplex B consisted of DXS7132, DXS6800, DXS6801, DXS7424, HPRTB, and DXS10011. The set of amplified X-STRs was designed to include groups of closely linked markers (DXS101-DXS7424 and DXS6789-DXS6801-DXS6809) to generate highly informative haplotypes for kinship testing. A population genetics study of the 12 X-STRs was conducted in a northwestern Italian population sample (n=160, 80 women and 80 men). A diallelic pattern at locus DXS6789 was observed in one man.
AB - Two multiplex polymerase chain reaction systems for the automated profiling of 12 X-chromosomal short tandem repeat (STR) markers were developed. Multiplex A consisted of DXS6789, DXS6809, GATA172D05, DXS101, DXS8378, and DXS8377. Multiplex B consisted of DXS7132, DXS6800, DXS6801, DXS7424, HPRTB, and DXS10011. The set of amplified X-STRs was designed to include groups of closely linked markers (DXS101-DXS7424 and DXS6789-DXS6801-DXS6809) to generate highly informative haplotypes for kinship testing. A population genetics study of the 12 X-STRs was conducted in a northwestern Italian population sample (n=160, 80 women and 80 men). A diallelic pattern at locus DXS6789 was observed in one man.
KW - DXS6789
KW - Italy
KW - Multiplex PCR
KW - Short tandem repeats
KW - X chromosome
UR - https://www.scopus.com/pages/publications/33747333889
U2 - 10.1007/s00414-006-0115-9
DO - 10.1007/s00414-006-0115-9
M3 - Article
SN - 0937-9827
VL - 120
SP - 315
EP - 318
JO - International Journal of Legal Medicine
JF - International Journal of Legal Medicine
IS - 5
ER -