Abstract
In critically ill patients, any acute organ injury is associated with a sudden change of circulating factors that may play a role in distant organ dysfunction through a complex cross-talk. In this issue, Virzì and colleagues discuss the relevance of humoral signalling between heart and kidney, focusing on type 1 and type 3 cardio-renal syndrome. We herein review the mechanisms of heart-kidney cross-talk, discussing the role of circulating detrimental mediators in the pathogenetic mechanisms of cardio-renal syndrome.
Lingua originale | Inglese |
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Numero di articolo | 404 |
Rivista | Critical Care |
Volume | 18 |
Numero di pubblicazione | 1 |
DOI |
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Stato di pubblicazione | Pubblicato - 22 gen 2014 |
Pubblicato esternamente | Sì |