Deprivazione di sonno ed eccitabilita corticale: Studio con stimolazione magnetica transcranica

C. Civardi; R. Cantello; P. Naldi; A. Cavalli; C. Varrasi; C. Comi; R. Tarletti; R. Vicentini; C. Boccagni; L. Bolamperti; F. Monaco

Deprivazione di sonno ed eccitabilita corticale: Studio con stimolazione magnetica transcranica

C. Civardi, R. Cantello, P. Naldi, A. Cavalli, C. Varrasi, C. Comi, R. Tarletti, R. Vicentini, C. Boccagni, L. Bolamperti, F. Monaco

Dipartimento di Medicina Traslazionale

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

By a single and paired-pulse transcranial magnetic stimulation (TMS) study, we measured the excitability of the primary motor cortex before and after sleep deprivation in seven normal subjects. We observed a significant (p<0.05) reduction of both inhibition and facilitation, as tested by paired- TMS, after sleep deprivation. These changes might be due to the alterations in the cerebral neurotransmitters that have been associated with sleep deprivation. They likely represent a substrate for the enhanced expression of electrical and clinical epileptic abnormalities after sleep deprivation.

Titolo tradotto del contributo	Changes of cortical excitability due to sleep deprivation: A transcranical magnetic stimulation study
Lingua originale	Italian
pagine (da-a)	159-161
Numero di pagine	3
Rivista	Bollettino - Lega Italiana contro l'Epilessia
Numero di pubblicazione	106-107
Stato di pubblicazione	Pubblicato - 1999

Keywords

Epilepsy
Motor Cortex Excitability
Sleep Deprivation
Transcranial Magnetic Stimulation

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abstract = "By a single and paired-pulse transcranial magnetic stimulation (TMS) study, we measured the excitability of the primary motor cortex before and after sleep deprivation in seven normal subjects. We observed a significant (p<0.05) reduction of both inhibition and facilitation, as tested by paired- TMS, after sleep deprivation. These changes might be due to the alterations in the cerebral neurotransmitters that have been associated with sleep deprivation. They likely represent a substrate for the enhanced expression of electrical and clinical epileptic abnormalities after sleep deprivation.",

keywords = "Epilepsy, Motor Cortex Excitability, Sleep Deprivation, Transcranial Magnetic Stimulation",

author = "C. Civardi and R. Cantello and P. Naldi and A. Cavalli and C. Varrasi and C. Comi and R. Tarletti and R. Vicentini and C. Boccagni and L. Bolamperti and F. Monaco",

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T1 - Deprivazione di sonno ed eccitabilita corticale

T2 - Studio con stimolazione magnetica transcranica

AU - Civardi, C.

AU - Cantello, R.

AU - Naldi, P.

AU - Cavalli, A.

AU - Varrasi, C.

AU - Comi, C.

AU - Tarletti, R.

AU - Vicentini, R.

AU - Boccagni, C.

AU - Bolamperti, L.

AU - Monaco, F.

PY - 1999

Y1 - 1999

N2 - By a single and paired-pulse transcranial magnetic stimulation (TMS) study, we measured the excitability of the primary motor cortex before and after sleep deprivation in seven normal subjects. We observed a significant (p<0.05) reduction of both inhibition and facilitation, as tested by paired- TMS, after sleep deprivation. These changes might be due to the alterations in the cerebral neurotransmitters that have been associated with sleep deprivation. They likely represent a substrate for the enhanced expression of electrical and clinical epileptic abnormalities after sleep deprivation.

AB - By a single and paired-pulse transcranial magnetic stimulation (TMS) study, we measured the excitability of the primary motor cortex before and after sleep deprivation in seven normal subjects. We observed a significant (p<0.05) reduction of both inhibition and facilitation, as tested by paired- TMS, after sleep deprivation. These changes might be due to the alterations in the cerebral neurotransmitters that have been associated with sleep deprivation. They likely represent a substrate for the enhanced expression of electrical and clinical epileptic abnormalities after sleep deprivation.

KW - Epilepsy

KW - Motor Cortex Excitability

KW - Sleep Deprivation

KW - Transcranial Magnetic Stimulation

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AN - SCOPUS:0033493247

SN - 0394-560X

SP - 159

EP - 161

JO - Bollettino - Lega Italiana contro l'Epilessia

JF - Bollettino - Lega Italiana contro l'Epilessia

IS - 106-107

ER -

Deprivazione di sonno ed eccitabilita corticale: Studio con stimolazione magnetica transcranica

Abstract

Keywords

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