Degenerate self-reactive human T-cell receptor causes spontaneous autoimmune disease in mice

Keyphrases

• T Cells 100%
• T Cell Receptor 100%
• Autoimmune Disease 100%
• Self-reactivity 100%
• Infiltrating T Cells 100%
• Genetically Modified T Cells 66%
• Pathologic 33%
• Autoantibodies 33%
• Organ-specific Autoimmune Diseases 33%
• Thyroiditis 33%
• Autoimmunity 33%
• Well-defined 33%
• Transgenic Mice 33%
• Autoimmune Thyroiditis 33%
• Co-expression 33%
• Epitope 33%
• Thyroid Peroxidase Antibody (TPOAb) 33%
• Human Leukocyte Antigen 33%
• Destructive Thyroiditis 33%
• Autoreactive T Cells 33%
• Histocompatibility 33%
• Humanized Models 33%
• Self-epitopes 33%
• Pathogenic Role 33%
• Autoimmune Hypothyroidism 33%
• Major Histocompatibility Complex Molecules 33%
• Human Pathogenic 33%

Immunology and Microbiology

• T Cell 100%
• T Cell Receptor 100%
• Autoimmune Disease 100%
• Epitope 28%
• Thyroiditis 28%
• Transgenics 28%
• Thyroid 28%
• Autoantibodies 14%
• Major Histocompatibility Complex 14%
• Autoimmunity 14%
• Transgenic Mouse 14%
• Autoimmune Thyroiditis 14%
• Leukocyte Antigen 14%
• Organ-Specific Autoimmune Disease 14%
• Histocompatibility 14%