TY - JOUR
T1 - De-escalation of breast radiotherapy after conserving surgery in low-risk early breast cancer patients
AU - Franco, Pierfrancesco
AU - Iorio, Giuseppe Carlo
AU - Bartoncini, Sara
AU - Airoldi, Mario
AU - De Sanctis, Corrado
AU - Castellano, Isabella
AU - Ricardi, Umberto
N1 - Publisher Copyright:
© 2018, Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2018/5/1
Y1 - 2018/5/1
N2 - The reduction in the burden related to treatment is becoming more and more important in modern oncology. Radiation therapy is a mainstay option in the postoperative setting for early breast cancer patients after breast-conserving surgery. Nowadays, different options are available to de-escalate radiotherapy in this scenario such as the use of hypofractionated whole-breast radiation, the selective delivery of the boost dose to the lumpectomy cavity, the introduction of accelerated partial breast irradiation and the omission of treatment in appropriately selected patients with low-risk features. We herein provide a review article on this topic.
AB - The reduction in the burden related to treatment is becoming more and more important in modern oncology. Radiation therapy is a mainstay option in the postoperative setting for early breast cancer patients after breast-conserving surgery. Nowadays, different options are available to de-escalate radiotherapy in this scenario such as the use of hypofractionated whole-breast radiation, the selective delivery of the boost dose to the lumpectomy cavity, the introduction of accelerated partial breast irradiation and the omission of treatment in appropriately selected patients with low-risk features. We herein provide a review article on this topic.
KW - Accelerated partial breast irradiation
KW - Boost
KW - Breast cancer
KW - De-escalation
KW - Hypofractionation
KW - Radiotherapy omission
KW - Whole-breast radiation
UR - http://www.scopus.com/inward/record.url?scp=85044957745&partnerID=8YFLogxK
U2 - 10.1007/s12032-018-1121-8
DO - 10.1007/s12032-018-1121-8
M3 - Review article
SN - 1357-0560
VL - 35
JO - Medical Oncology
JF - Medical Oncology
IS - 5
M1 - 62
ER -