Correlation between new OCT parameters and metamorphopsia in advanced stages of epiretinal membranes

M. Alkabes, P. Fogagnolo, S. Vujosevic, L. Rossetti, G. Casini, STEFANO DE CILLA'

Risultato della ricerca: Contributo su rivistaArticolo in rivistapeer review

Abstract

Purpose: To correlate metamorphopsia provided by M-CHARTS and ectopic inner foveal layers (EIFL) or ‘central bouquet’ abnormality (CBA) in patients with advanced stages of epiretinal membrane (ERM) following the novel Optical Coherence Tomography (OCT)-based grading scheme. Methods: In 60 eyes of 57 patients affected by ERM (stages 3 and 4), the degree of metamorphopsia using the M-CHARTS was evaluated (M-SCORE) and correlated with EIFL, CBA and central foveal thickness (CFT) as measured on OCT scans. Results: A total of 37 and 23 eyes were diagnosed having ERM stages 3 and 4, respectively. Mean vertical and horizontal M-SCORE (M-V and M-H) were 0.64 ± 0.43 and 0.58 ± 0.37 standard deviations, respectively. Mean M-SCORE exhibited a statistically significant correlation with EIFL and CFT (both p < 0.0001), but not with CBA (p = 0.84). Analysing the direction of metamorphopsia separately, M-H and M-V were significantly correlated with EIFL (both p < 0.0001), but not with CBA thickness (p = 0.70 and 0.33 respectively). Ectopic inner foveal layers (EIFL) was significantly influenced by the presence of CBA (CBA present, 158.29 ± 63.53 micron; CBA absent, 107.05 ± 94.13 micron, p = 0.04). No significant differences were found for both M-V and M-H with respect to the presence of CBA. Conclusions: Based on the novel OCT-based grading scheme for ERMs, our results demonstrate that EIFL, but not CBA, might be considered a good indicator for metamorphopsia in patients with advanced ERMs.
Lingua originaleInglese
pagine (da-a)780-786
Numero di pagine7
RivistaActa Ophthalmologica
Volume98
Numero di pubblicazione8
DOI
Stato di pubblicazionePubblicato - 2020

Keywords

  • Aged
  • Epiretinal Membrane
  • Female
  • Follow-Up Studies
  • Fovea Centralis
  • Humans
  • M-CHARTS
  • Male
  • OCT
  • Retrospective Studies
  • Severity of Illness Index
  • Tomography, Optical Coherence
  • Vision Disorders
  • Visual Acuity
  • central bouquet
  • ectopic inner foveal layer
  • epiretinal membrane
  • metamorphopsia

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