TY - JOUR
T1 - Contemporary Assessment of Survival Rates in Stage I Testicular Seminoma
T2 - A Population-Based Comparison Between Surveillance and Active Treatment After Orchiectomy
AU - Mistretta, Francesco A.
AU - Mazzone, Elio
AU - Palumbo, Carlotta
AU - Knipper, Sophie
AU - Tian, Zhe
AU - Nazzani, Sebastiano
AU - Lattouf, Jean Baptiste
AU - Musi, Gennaro
AU - Perrotte, Paul
AU - Montanari, Emanuele
AU - Shariat, Shahrokh F.
AU - Montorsi, Francesco
AU - Saad, Fred
AU - de Cobelli, Ottavio
AU - Karakiewicz, Pierre I.
N1 - Publisher Copyright:
© 2019 Elsevier Inc.
PY - 2019/8
Y1 - 2019/8
N2 - Within the Surveillance, Epidemiology, and End Results database (1988-2015) we identified 11,206 stage I testicular seminoma patients, who underwent respectively surveillance (40%), chemotherapy (CHT; 8%), or radiotherapy (RT; 52%) after orchiectomy. Surveillance and CHT rates increased over time, whereas RT rates decreased. A protective effect of active treatment defined as either RT or CHT was identified on cancer-specific mortality, relative to surveillance.
AB - Within the Surveillance, Epidemiology, and End Results database (1988-2015) we identified 11,206 stage I testicular seminoma patients, who underwent respectively surveillance (40%), chemotherapy (CHT; 8%), or radiotherapy (RT; 52%) after orchiectomy. Surveillance and CHT rates increased over time, whereas RT rates decreased. A protective effect of active treatment defined as either RT or CHT was identified on cancer-specific mortality, relative to surveillance.
KW - Chemotherapy
KW - Radiotherapy
KW - SEER program
KW - Surveillance
KW - Testicular neoplasm
UR - https://www.scopus.com/pages/publications/85066808004
U2 - 10.1016/j.clgc.2019.04.015
DO - 10.1016/j.clgc.2019.04.015
M3 - Article
SN - 1558-7673
VL - 17
SP - e793-e801
JO - Clinical Genitourinary Cancer
JF - Clinical Genitourinary Cancer
IS - 4
ER -