Computational Methods for the Discovery and Optimization of TAAR1 and TAAR5 Ligands

Keyphrases

• Computational Methods 100%
• Trace Amine-associated Receptor 1 (TAAR1) 100%
• TAAR5 100%
• G Protein-coupled Receptor 28%
• Species Traits 28%
• Druggable Targets 14%
• Chemotype 14%
• New Ligand 14%
• Drug Discovery 14%
• Central Nervous System 14%
• Physiological Function 14%
• Drug Design 14%
• Olfactory Receptor 14%
• Drug pipeline 14%
• Brain Function 14%
• Selective Ligands 14%
• Homology Modeling 14%
• Endogenous Ligand 14%
• Computational Effort 14%
• Modeling Method 14%
• Synthetic Ligands 14%
• Ligand-based Methods 14%

Pharmacology, Toxicology and Pharmaceutical Science

• Receptor 100%
• Drug Discovery 100%
• G Protein Coupled Receptor 100%
• Drug Development 50%
• Murine 50%
• Diseases 50%

Biochemistry, Genetics and Molecular Biology

• TAAR1 100%
• G Protein Coupled Receptor 33%
• Species Difference 33%
• Olfactory Receptor 16%
• Murine 16%
• Brain Function 16%
• Homology Modeling 16%
• Trace Amine-Associated Receptor 16%