Comparative effects of estrogens and prolactin on nigral and striatal GAD activity

Fernando Nicoletti; Francesco Patti; Napoleone Ferrara; Pier Luigi Canonico; Giovanni Giammona; Daniele Filippo Condorelli; Umberto Scapagnini

doi:10.1016/0006-8993(82)90633-3

Comparative effects of estrogens and prolactin on nigral and striatal GAD activity

Fernando Nicoletti, Francesco Patti, Napoleone Ferrara, Pier Luigi Canonico, Giovanni Giammona, Daniele Filippo Condorelli, Umberto Scapagnini

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

The comparative effects of a 10 day estrogen treatment and estrogen independent hyperprolactinemia on nigral and striatal glutamic acid decarboxylase (GAD, EC 4.1.1.15) activity were investigated in male rats. Data obtained show that estrogen treatment decreases GAD activity in substantia nigra, while an increase was observed in conditions of hyperprolactinemia induced by modulation of strio-nigral GABAergic system by estrogens and prolactin is suggested.

Lingua originale	Inglese
pagine (da-a)	238-241
Numero di pagine	4
Rivista	Brain Research
Volume	232
Numero di pubblicazione	1
DOI	https://doi.org/10.1016/0006-8993(82)90633-3
Stato di pubblicazione	Pubblicato - 28 gen 1982
Pubblicato esternamente	Sì

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10.1016/0006-8993(82)90633-3

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title = "Comparative effects of estrogens and prolactin on nigral and striatal GAD activity",

abstract = "The comparative effects of a 10 day estrogen treatment and estrogen independent hyperprolactinemia on nigral and striatal glutamic acid decarboxylase (GAD, EC 4.1.1.15) activity were investigated in male rats. Data obtained show that estrogen treatment decreases GAD activity in substantia nigra, while an increase was observed in conditions of hyperprolactinemia induced by modulation of strio-nigral GABAergic system by estrogens and prolactin is suggested.",

keywords = "GAD activity, corpus striatum, estrogens, prolactin, substantia nigra",

author = "Fernando Nicoletti and Francesco Patti and Napoleone Ferrara and Canonico, \{Pier Luigi\} and Giovanni Giammona and Condorelli, \{Daniele Filippo\} and Umberto Scapagnini",

year = "1982",

month = jan,

day = "28",

doi = "10.1016/0006-8993(82)90633-3",

language = "English",

volume = "232",

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journal = "Brain Research",

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T1 - Comparative effects of estrogens and prolactin on nigral and striatal GAD activity

AU - Nicoletti, Fernando

AU - Patti, Francesco

AU - Ferrara, Napoleone

AU - Canonico, Pier Luigi

AU - Giammona, Giovanni

AU - Condorelli, Daniele Filippo

AU - Scapagnini, Umberto

PY - 1982/1/28

Y1 - 1982/1/28

N2 - The comparative effects of a 10 day estrogen treatment and estrogen independent hyperprolactinemia on nigral and striatal glutamic acid decarboxylase (GAD, EC 4.1.1.15) activity were investigated in male rats. Data obtained show that estrogen treatment decreases GAD activity in substantia nigra, while an increase was observed in conditions of hyperprolactinemia induced by modulation of strio-nigral GABAergic system by estrogens and prolactin is suggested.

AB - The comparative effects of a 10 day estrogen treatment and estrogen independent hyperprolactinemia on nigral and striatal glutamic acid decarboxylase (GAD, EC 4.1.1.15) activity were investigated in male rats. Data obtained show that estrogen treatment decreases GAD activity in substantia nigra, while an increase was observed in conditions of hyperprolactinemia induced by modulation of strio-nigral GABAergic system by estrogens and prolactin is suggested.

KW - GAD activity

KW - corpus striatum

KW - estrogens

KW - prolactin

KW - substantia nigra

UR - https://www.scopus.com/pages/publications/0020043326

U2 - 10.1016/0006-8993(82)90633-3

DO - 10.1016/0006-8993(82)90633-3

M3 - Article

SN - 0006-8993

VL - 232

SP - 238

EP - 241

JO - Brain Research

JF - Brain Research

IS - 1

ER -

Comparative effects of estrogens and prolactin on nigral and striatal GAD activity

Abstract

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