Clues on Balo's concentric sclerosis evolution from serial analysis of ADC values

Paolo Ripellino; Roman Khonsari; Alessandro Stecco; Massimo Filippi; Marco Perchinunno; Roberto Cantello

doi:10.3109/00207454.2014.989524

Clues on Balo's concentric sclerosis evolution from serial analysis of ADC values

Paolo Ripellino, Roman Khonsari, Alessandro Stecco, Massimo Filippi, Marco Perchinunno, Roberto Cantello

Dipartimento di Medicina Traslazionale

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

Balò's sclerosis is considered a rare variant of multiple sclerosis characterized by demyelination with concentric rings. Advanced magnetic resonance studies allow nowadays early diagnosis and prompt treatment. However, the pathophysiology of lesion evolution is still matter of debate, as detailed in our literature review. Based on a clear-cut Balò's lesion analysis, we describe early changes in DWI and ADC values within the different layers, favoring the concept of a centrifugal growth.

Lingua originale	Inglese
pagine (da-a)	88-95
Numero di pagine	8
Rivista	International Journal of Neuroscience
Volume	126
Numero di pubblicazione	1
DOI	https://doi.org/10.3109/00207454.2014.989524
Stato di pubblicazione	Pubblicato - 2 gen 2016

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10.3109/00207454.2014.989524

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title = "Clues on Balo's concentric sclerosis evolution from serial analysis of ADC values",

abstract = "Bal{\`o}'s sclerosis is considered a rare variant of multiple sclerosis characterized by demyelination with concentric rings. Advanced magnetic resonance studies allow nowadays early diagnosis and prompt treatment. However, the pathophysiology of lesion evolution is still matter of debate, as detailed in our literature review. Based on a clear-cut Bal{\`o}'s lesion analysis, we describe early changes in DWI and ADC values within the different layers, favoring the concept of a centrifugal growth.",

keywords = "ADC, Bal{\`o}'s sclerosis, MRI, concentric sclerosis, diffusion",

author = "Paolo Ripellino and Roman Khonsari and Alessandro Stecco and Massimo Filippi and Marco Perchinunno and Roberto Cantello",

note = "Publisher Copyright: Copyright {\textcopyright} 2014 Taylor and Francis.",

year = "2016",

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AU - Khonsari, Roman

AU - Stecco, Alessandro

AU - Filippi, Massimo

AU - Perchinunno, Marco

AU - Cantello, Roberto

PY - 2016/1/2

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N2 - Balò's sclerosis is considered a rare variant of multiple sclerosis characterized by demyelination with concentric rings. Advanced magnetic resonance studies allow nowadays early diagnosis and prompt treatment. However, the pathophysiology of lesion evolution is still matter of debate, as detailed in our literature review. Based on a clear-cut Balò's lesion analysis, we describe early changes in DWI and ADC values within the different layers, favoring the concept of a centrifugal growth.

AB - Balò's sclerosis is considered a rare variant of multiple sclerosis characterized by demyelination with concentric rings. Advanced magnetic resonance studies allow nowadays early diagnosis and prompt treatment. However, the pathophysiology of lesion evolution is still matter of debate, as detailed in our literature review. Based on a clear-cut Balò's lesion analysis, we describe early changes in DWI and ADC values within the different layers, favoring the concept of a centrifugal growth.

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KW - Balò's sclerosis

KW - MRI

KW - concentric sclerosis

KW - diffusion

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Clues on Balo's concentric sclerosis evolution from serial analysis of ADC values

Abstract

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