Cloning of the gene coding for human l apoferritin

Claudio Santoro; Maria Marone; Marina Ferrone; Francesco Costanzo; Maurizio Colombo; Carlo Minganti; Riccardo Cortese; Lorenzo Silengo

doi:10.1093/nar/14.7.2863

Cloning of the gene coding for human l apoferritin

Claudio Santoro, Maria Marone, Marina Ferrone, Francesco Costanzo, Maurizio Colombo, Carlo Minganti, Riccardo Cortese, Lorenzo Silengo

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

A recently reported cDNA clone coding for human promyelocytic L apoferritin, shows some differences with a liver L apoferritin cDNA. We have investigated if these differences are due to the expression of different genes or to an alternative transcription of an unique gene. In this paper we report data suggesting that a single gene is mainly expressed in several tissues examined. This gene has been cloned and characterized. Its sequence shows three introns: the exon sequence is identical to that of cDNA clone isolated from human liver. A minimum of five related pseudogenes have been also analysed. One of them is a processed pseudogene interrupted by an intron-like fragment.

Lingua originale	Inglese
pagine (da-a)	2863-2876
Numero di pagine	14
Rivista	Nucleic Acids Research
Volume	14
Numero di pubblicazione	7
DOI	https://doi.org/10.1093/nar/14.7.2863
Stato di pubblicazione	Pubblicato - 11 apr 1986
Pubblicato esternamente	Sì

Accesso al documento

10.1093/nar/14.7.2863

Altri file e collegamenti

Link to publication in Scopus

Cita questo

@article{9a0a6dd5b1df4c7d8473b839a8823e25,

title = "Cloning of the gene coding for human l apoferritin",

abstract = "A recently reported cDNA clone coding for human promyelocytic L apoferritin, shows some differences with a liver L apoferritin cDNA. We have investigated if these differences are due to the expression of different genes or to an alternative transcription of an unique gene. In this paper we report data suggesting that a single gene is mainly expressed in several tissues examined. This gene has been cloned and characterized. Its sequence shows three introns: the exon sequence is identical to that of cDNA clone isolated from human liver. A minimum of five related pseudogenes have been also analysed. One of them is a processed pseudogene interrupted by an intron-like fragment.",

author = "Claudio Santoro and Maria Marone and Marina Ferrone and Francesco Costanzo and Maurizio Colombo and Carlo Minganti and Riccardo Cortese and Lorenzo Silengo",

note = "Funding Information: ACKNOWLEDGMENTS We are particularly grateful to Dr. C. Ponzetto for revising the manuscript. M.M. was in part supported by a fellowship from Anna Villa Rusconi Foundation. This work was supported by P.F. Ingegneria Genetica, CNR, Rome.",

year = "1986",

month = apr,

day = "11",

doi = "10.1093/nar/14.7.2863",

language = "English",

volume = "14",

pages = "2863--2876",

journal = "Nucleic Acids Research",

issn = "0305-1048",

publisher = "Oxford University Press",

number = "7",

}

TY - JOUR

T1 - Cloning of the gene coding for human l apoferritin

AU - Santoro, Claudio

AU - Marone, Maria

AU - Ferrone, Marina

AU - Costanzo, Francesco

AU - Colombo, Maurizio

AU - Minganti, Carlo

AU - Cortese, Riccardo

AU - Silengo, Lorenzo

N1 - Funding Information: ACKNOWLEDGMENTS We are particularly grateful to Dr. C. Ponzetto for revising the manuscript. M.M. was in part supported by a fellowship from Anna Villa Rusconi Foundation. This work was supported by P.F. Ingegneria Genetica, CNR, Rome.

PY - 1986/4/11

Y1 - 1986/4/11

N2 - A recently reported cDNA clone coding for human promyelocytic L apoferritin, shows some differences with a liver L apoferritin cDNA. We have investigated if these differences are due to the expression of different genes or to an alternative transcription of an unique gene. In this paper we report data suggesting that a single gene is mainly expressed in several tissues examined. This gene has been cloned and characterized. Its sequence shows three introns: the exon sequence is identical to that of cDNA clone isolated from human liver. A minimum of five related pseudogenes have been also analysed. One of them is a processed pseudogene interrupted by an intron-like fragment.

AB - A recently reported cDNA clone coding for human promyelocytic L apoferritin, shows some differences with a liver L apoferritin cDNA. We have investigated if these differences are due to the expression of different genes or to an alternative transcription of an unique gene. In this paper we report data suggesting that a single gene is mainly expressed in several tissues examined. This gene has been cloned and characterized. Its sequence shows three introns: the exon sequence is identical to that of cDNA clone isolated from human liver. A minimum of five related pseudogenes have been also analysed. One of them is a processed pseudogene interrupted by an intron-like fragment.

UR - http://www.scopus.com/inward/record.url?scp=0022580072&partnerID=8YFLogxK

U2 - 10.1093/nar/14.7.2863

DO - 10.1093/nar/14.7.2863

M3 - Article

SN - 0305-1048

VL - 14

SP - 2863

EP - 2876

JO - Nucleic Acids Research

JF - Nucleic Acids Research

IS - 7

ER -

Cloning of the gene coding for human l apoferritin

Abstract

Accesso al documento

Altri file e collegamenti

Fingerprint

Cita questo