Charged molecular silica trigger in vitro NETosis in human granulocytes via both oxidative and autophagic pathways

Risultato della ricerca: Contributo su rivistaArticolo in rivistapeer review

Abstract

Neutrophils play a key role in immunity and are known to respond to exogenous threats by releasing neutrophil extracellular traps (NETs) through NETosis, a process involving the release of neutrophils nuclear DNA decorated with proteins into the extracellular space. In this study, attention has been focused on the ability of differently charged molecular systems polyhedral oligomeric silsesquioxanes (POSS) to induce NETosis.
Lingua originaleInglese
pagine (da-a)7058-7068
RivistaEuropean Review for Medical and Pharmacological Sciences
Volume22
Numero di pubblicazione20
Stato di pubblicazionePubblicato - 2018

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