TY - JOUR
T1 - Cerebral venous thrombosis
T2 - A retrospective multicentre study of 48 patients
AU - Terazzi, E.
AU - Mittino, D.
AU - Rudà, R.
AU - Cerrato, P.
AU - Monaco, F.
AU - Sciolla, R.
AU - Grasso, E.
AU - Leone, M. A.
AU - De Mattei, M.
AU - Verdun, E.
AU - Giraudo, M.
AU - Gerbino-Promis, P.
AU - Appiotti, A.
AU - Gai, P.
AU - Bottacchi, E.
AU - Labate, C.
AU - Villani, A.
AU - Pavanelli, E.
AU - Ferrari, G.
AU - Provera, P.
PY - 2005/2
Y1 - 2005/2
N2 - The objective was to describe the clinical features and management of cerebral venous thrombosis (CVT) in non-selected centres. An observational study in 11 neurological departments in NW Italy was carried out from 1995 through 1999 on 38 female and 10 male patients. Mean age: 44.8 years, SD=14.3. Onset: acute in 21 patients (44%), subacute in 17 (35%) and chronic in 10 (21%). Most frequent onset: with focal deficits and/or seizures, followed by impaired consciousness or confusion, isolated headache, isolated intracranial hypertension and cavernous syndrome. No risk factor was found in 8 patients (17%). The superior sagittal sinus was involved in 27 patients (56%) and the transverse sinus in 29 (60%). Anticoagulants were used in 45 patients (94%). Rankin Scale score at discharge: 0 (27 patients), 1 (four), 2 (five), 3 (five), 4 (none), 5 (one) and six were dead. Thirteen patients had deep CVT: age, risk factors, neurological signs and outcome differed from cortical CVT (35 patients), although not significantly. Clinical features, risk factors and outcome of CVT patients from non-selected centres are similar to those from specialised centres.
AB - The objective was to describe the clinical features and management of cerebral venous thrombosis (CVT) in non-selected centres. An observational study in 11 neurological departments in NW Italy was carried out from 1995 through 1999 on 38 female and 10 male patients. Mean age: 44.8 years, SD=14.3. Onset: acute in 21 patients (44%), subacute in 17 (35%) and chronic in 10 (21%). Most frequent onset: with focal deficits and/or seizures, followed by impaired consciousness or confusion, isolated headache, isolated intracranial hypertension and cavernous syndrome. No risk factor was found in 8 patients (17%). The superior sagittal sinus was involved in 27 patients (56%) and the transverse sinus in 29 (60%). Anticoagulants were used in 45 patients (94%). Rankin Scale score at discharge: 0 (27 patients), 1 (four), 2 (five), 3 (five), 4 (none), 5 (one) and six were dead. Thirteen patients had deep CVT: age, risk factors, neurological signs and outcome differed from cortical CVT (35 patients), although not significantly. Clinical features, risk factors and outcome of CVT patients from non-selected centres are similar to those from specialised centres.
KW - Cerebral venous thrombosis
KW - Headache
KW - Multicentre studies
KW - Risk factors
KW - Seizures
UR - http://www.scopus.com/inward/record.url?scp=20044389070&partnerID=8YFLogxK
U2 - 10.1007/s10072-004-0363-8
DO - 10.1007/s10072-004-0363-8
M3 - Article
SN - 1590-1874
VL - 25
SP - 311
EP - 315
JO - Neurological Sciences
JF - Neurological Sciences
IS - 6
ER -