Carbon tetrachloride-induced inhibition of hepatocyte lipoprotein secretion: Functional impairment of Golgi apparatus in the early phases of such injury

Giuseppe Poli, Elena Chiarpotto, Emanuele Albano, Damiano Cottalasso, Giorgio Nanni, Umberto M. Marinari, Anna M. Bassi, Mario U. Dianzani

Risultato della ricerca: Contributo su rivistaArticolo in rivistapeer review

Abstract

Functional change of liver Golgi apparatus during carbon tetrachloride (CCl4) poisoning was demonstrated both in rat isolated hepatocytes and in the whole animal. The "in vitro" experimental model provided evidence of Golgi derangement early after giving the haloalkane. The "in vivo" analyses also showed that such an alteration involves both formative and secretory sides of the subcellular structure.

Lingua originaleInglese
pagine (da-a)533-539
Numero di pagine7
RivistaLife Sciences
Volume36
Numero di pubblicazione6
DOI
Stato di pubblicazionePubblicato - 11 feb 1985
Pubblicato esternamente

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