TY - JOUR
T1 - Burden of mortality from asbestos‐related diseases in italy
AU - Fazzo, Lucia
AU - Binazzi, Alessandra
AU - Ferrante, Daniela
AU - Minelli, Giada
AU - Consonni, Dario
AU - Bauleo, Lisa
AU - Bruno, Caterina
AU - Bugani, Marcella
AU - Santis, Marco De
AU - Iavarone, Ivano
AU - Magnani, Corrado
AU - Romeo, Elisa
AU - Zona, Amerigo
AU - Alessi, Mariano
AU - Comba, Pietro
AU - Marinaccio, Alessandro
N1 - Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/10/1
Y1 - 2021/10/1
N2 - Asbestos is one of the major worldwide occupational carcinogens. The global burden of asbestos‐related diseases (ARDs) was estimated around 231,000 cases/year. Italy was one of the main European asbestos producers until the 1992 ban. The WHO recommended national programs, including epidemiological surveillance, to eliminate ARDs. The present paper shows the estimate of the burden of mortality from ARDs in Italy, established for the first time. National standardized rates of mortality from mesothelioma and asbestosis and their temporal trends, based on the National Institute of Statistics database, were computed. Deaths from lung cancer attributable to asbestos exposure were estimated using population‐based case‐control studies. Asbestos‐related lung and ovarian cancer deaths attributable to occupational exposure were estimated, considering the Italian occupational cohort studies. In the 2010–2016 period, 4400 deaths/year attributable to asbestos were estimated: 1515 from mesothelioma, 58 from asbestosis, 2830 from lung and 16 from ovarian cancers. The estimates based on occupational cohorts showed that each year 271 deaths from mesothelioma, 302 from lung cancer and 16 from ovarian cancer were attributable to occupational asbestos exposure in industrial sectors with high asbestos levels. The important health impact of asbestos in Italy, 10–25 years after the ban, was highlighted. These results suggest the need for appropriate interventions in terms of prevention, health care and social security at the local level and could contribute to the global estimate of ARDs.
AB - Asbestos is one of the major worldwide occupational carcinogens. The global burden of asbestos‐related diseases (ARDs) was estimated around 231,000 cases/year. Italy was one of the main European asbestos producers until the 1992 ban. The WHO recommended national programs, including epidemiological surveillance, to eliminate ARDs. The present paper shows the estimate of the burden of mortality from ARDs in Italy, established for the first time. National standardized rates of mortality from mesothelioma and asbestosis and their temporal trends, based on the National Institute of Statistics database, were computed. Deaths from lung cancer attributable to asbestos exposure were estimated using population‐based case‐control studies. Asbestos‐related lung and ovarian cancer deaths attributable to occupational exposure were estimated, considering the Italian occupational cohort studies. In the 2010–2016 period, 4400 deaths/year attributable to asbestos were estimated: 1515 from mesothelioma, 58 from asbestosis, 2830 from lung and 16 from ovarian cancers. The estimates based on occupational cohorts showed that each year 271 deaths from mesothelioma, 302 from lung cancer and 16 from ovarian cancer were attributable to occupational asbestos exposure in industrial sectors with high asbestos levels. The important health impact of asbestos in Italy, 10–25 years after the ban, was highlighted. These results suggest the need for appropriate interventions in terms of prevention, health care and social security at the local level and could contribute to the global estimate of ARDs.
KW - Asbestos
KW - Asbestosis
KW - Asbestos‐related diseases
KW - Burden of mortality
KW - Lung cancer
KW - Mesothelioma
UR - http://www.scopus.com/inward/record.url?scp=85115390909&partnerID=8YFLogxK
U2 - 10.3390/ijerph181910012
DO - 10.3390/ijerph181910012
M3 - Article
SN - 1661-7827
VL - 18
JO - International Journal of Environmental Research and Public Health
JF - International Journal of Environmental Research and Public Health
IS - 19
M1 - 12
ER -