TY - JOUR
T1 - Bilateral breast radiation delivered with static angle tomotherapy (TomoDirect)
T2 - Clinical feasibility and dosimetric results of a single patient
AU - Franco, Pierfrancesco
AU - Migliaccio, Fernanda
AU - Torielli, Paolo
AU - Sciacero, Piera
AU - Girelli, Giuseppe
AU - Cante, Domenico
AU - Arrichiello, Cecilia
AU - Borca, Valeria Casanova
AU - Cornetto, Andrea Peruzzo
AU - Numico, Gianmauro
AU - La Porta, Maria Rosa
AU - Tofani, Santi
AU - Ricardi, Umberto
N1 - Publisher Copyright:
© 2015 INTM, Italy. Published by Wichtig Publishing.
PY - 2015/1/1
Y1 - 2015/1/1
N2 - We herein report on a case of synchronous bilateral breast cancer patient undergoing adjuvant intensity-modulated whole breast with static angle tomotherapy (TomoDirect). The patient was treated with a hypofractionated schedule employing a simultaneous integrated boost approach. Radiotherapy schedule was 45 Gy/20 fractions (2.25 Gy daily) to the bilateral whole breast and 50 Gy/20 fractions (2.5 Gy daily) to the 2 lumpectomy cavities. Treatment was delivered over 4 weeks. Dosimetric results were robust with consistent target coverage and adequate normal tissue avoidance. Treatment was generally well-tolerated and acute toxicity profile was mild. The present report highlights the promising clinical feasibility of TomoDirect for bilateral breast irradiation.
AB - We herein report on a case of synchronous bilateral breast cancer patient undergoing adjuvant intensity-modulated whole breast with static angle tomotherapy (TomoDirect). The patient was treated with a hypofractionated schedule employing a simultaneous integrated boost approach. Radiotherapy schedule was 45 Gy/20 fractions (2.25 Gy daily) to the bilateral whole breast and 50 Gy/20 fractions (2.5 Gy daily) to the 2 lumpectomy cavities. Treatment was delivered over 4 weeks. Dosimetric results were robust with consistent target coverage and adequate normal tissue avoidance. Treatment was generally well-tolerated and acute toxicity profile was mild. The present report highlights the promising clinical feasibility of TomoDirect for bilateral breast irradiation.
KW - Adjuvant whole breast radiotherapy
KW - Bilateral breast cancer
KW - Hypofractionation
KW - Simultaneous integrated boost
KW - Tomotherapy
UR - http://www.scopus.com/inward/record.url?scp=84930715124&partnerID=8YFLogxK
U2 - 10.5301/tj.5000264
DO - 10.5301/tj.5000264
M3 - Article
SN - 0300-8916
VL - 101
SP - e4-e8
JO - Tumori
JF - Tumori
IS - 1
ER -
