ATM and chronic lymphocytic leukemia: Mutations, and not only deletions, matter

Davide Rossi; Gianluca Gaidano

doi:10.3324/haematol.2011.057109

ATM and chronic lymphocytic leukemia: Mutations, and not only deletions, matter

Davide Rossi, Gianluca Gaidano

Dipartimento di Medicina Traslazionale

Risultato della ricerca: Contributo su rivista › Editoriale

Abstract

ATM gene alterations in chronic lymphocytic leukemia patients induce a distinct gene expression profile and predict disease progression. [Haematologica. 2012]ATM gene alterations in chronic lymphocytic leukemia patients induce a distinct gene expression profile and predict disease progression. Guarini A, Marinelli M, Tavolaro S, Bellacchio E, Magliozzi M, Chiaretti S, De Propris MS, Peragine N, Santangelo S, Paoloni F, et al. Haematologica. 2012 Jan; 97(1):47-55. Epub 2011 Oct 11. ATM germline heterozygosity does not play a role in chronic lymphocytic leukemia initiation but influences rapid disease progression through loss of the remaining ATM allele.

Lingua originale	Inglese
pagine (da-a)	5-8
Numero di pagine	4
Rivista	Haematologica
Volume	97
Numero di pubblicazione	1
DOI	https://doi.org/10.3324/haematol.2011.057109
Stato di pubblicazione	Pubblicato - 1 gen 2012

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10.3324/haematol.2011.057109

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abstract = "ATM gene alterations in chronic lymphocytic leukemia patients induce a distinct gene expression profile and predict disease progression. [Haematologica. 2012]ATM gene alterations in chronic lymphocytic leukemia patients induce a distinct gene expression profile and predict disease progression. Guarini A, Marinelli M, Tavolaro S, Bellacchio E, Magliozzi M, Chiaretti S, De Propris MS, Peragine N, Santangelo S, Paoloni F, et al. Haematologica. 2012 Jan; 97(1):47-55. Epub 2011 Oct 11. ATM germline heterozygosity does not play a role in chronic lymphocytic leukemia initiation but influences rapid disease progression through loss of the remaining ATM allele.",

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N2 - ATM gene alterations in chronic lymphocytic leukemia patients induce a distinct gene expression profile and predict disease progression. [Haematologica. 2012]ATM gene alterations in chronic lymphocytic leukemia patients induce a distinct gene expression profile and predict disease progression. Guarini A, Marinelli M, Tavolaro S, Bellacchio E, Magliozzi M, Chiaretti S, De Propris MS, Peragine N, Santangelo S, Paoloni F, et al. Haematologica. 2012 Jan; 97(1):47-55. Epub 2011 Oct 11. ATM germline heterozygosity does not play a role in chronic lymphocytic leukemia initiation but influences rapid disease progression through loss of the remaining ATM allele.

AB - ATM gene alterations in chronic lymphocytic leukemia patients induce a distinct gene expression profile and predict disease progression. [Haematologica. 2012]ATM gene alterations in chronic lymphocytic leukemia patients induce a distinct gene expression profile and predict disease progression. Guarini A, Marinelli M, Tavolaro S, Bellacchio E, Magliozzi M, Chiaretti S, De Propris MS, Peragine N, Santangelo S, Paoloni F, et al. Haematologica. 2012 Jan; 97(1):47-55. Epub 2011 Oct 11. ATM germline heterozygosity does not play a role in chronic lymphocytic leukemia initiation but influences rapid disease progression through loss of the remaining ATM allele.

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ATM and chronic lymphocytic leukemia: Mutations, and not only deletions, matter

Abstract

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