Application of the Ugi four-component reaction to the synthesis of ditopic bifunctional chelating agents

Keyphrases

• Monoamide 100%
• Bifunctional Chelating Agent 100%
• Ditopic 100%
• Ugi Four-component Reaction 100%
• Relaxivity 66%
• Amino 66%
• Functional Groups 33%
• Chelates 33%
• Aqueous Media 33%
• Bifunctional 33%
• Methanol 33%
• Human Serum Albumin 33%
• Conjugation 33%
• Chelator 33%
• Magnetic Field Strength 33%
• Gd(III) 33%
• Affinity Constant 33%
• Biomolecules 33%
• Temperature Field 33%
• Aldehydes 33%
• Isocyanide 33%
• Cyclohexyl 33%
• Lipophilic Complex 33%
• Complex Forms 33%
• Proton Relaxometry 33%
• Ultrasound Irradiation 33%
• Octadecyl 33%
• Optimal Reaction Conditions 33%
• Dimeric Ligands 33%
• Varying Temperature 33%

Chemistry

• DOTA 100%
• Chelating Agent 100%
• Methanol 33%
• Magnetic Field 33%
• Kd 33%
• Isocyanide 33%
• Ultrasound Irradiation 33%
• chelate 33%
• Micelle 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Chelating Agent 100%
• Tetraxetan 100%
• Functional Groups 33%
• Chelate 33%
• Methanol 33%
• Human Serum Albumin 33%
• Isocyanide 33%
• Micelle 33%