Application of induced pluripotent stem cell technology to the study of hematological diseases

Mailin Li; Pasquale Cascino; Simone Ummarino; Annalisa Di Ruscio

doi:10.3390/cells6010007

Application of induced pluripotent stem cell technology to the study of hematological diseases

Mailin Li, Pasquale Cascino, Simone Ummarino, Annalisa Di Ruscio

Risultato della ricerca: Contributo su rivista › Articolo di review › peer review

Abstract

The burst of reprogramming technology in recent years has revolutionized the field of stem cell biology, offering new opportunities for personalized, regenerative therapies. The direct reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) has provided an invaluable tool to study and model a wide range of human diseases. Here, we review the transforming potential of such a strategy in research and in therapies applicable to the hematology field.

Lingua originale	Inglese
Numero di articolo	7
Rivista	Cells
Volume	6
Numero di pubblicazione	1
DOI	https://doi.org/10.3390/cells6010007
Stato di pubblicazione	Pubblicato - 8 mar 2017
Pubblicato esternamente	Sì

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10.3390/cells6010007

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title = "Application of induced pluripotent stem cell technology to the study of hematological diseases",

abstract = "The burst of reprogramming technology in recent years has revolutionized the field of stem cell biology, offering new opportunities for personalized, regenerative therapies. The direct reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) has provided an invaluable tool to study and model a wide range of human diseases. Here, we review the transforming potential of such a strategy in research and in therapies applicable to the hematology field.",

keywords = "Blood diseases, Cancer, Regenerative medicine, Reprogramming",

author = "Mailin Li and Pasquale Cascino and Simone Ummarino and {Di Ruscio}, Annalisa",

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AB - The burst of reprogramming technology in recent years has revolutionized the field of stem cell biology, offering new opportunities for personalized, regenerative therapies. The direct reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) has provided an invaluable tool to study and model a wide range of human diseases. Here, we review the transforming potential of such a strategy in research and in therapies applicable to the hematology field.

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KW - Cancer

KW - Regenerative medicine

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Application of induced pluripotent stem cell technology to the study of hematological diseases

Abstract

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