Abstract
Capitalizing on in situ activation with the cyclic phosphonic anhydride PPAA (1), the conversion of carboxylic acids into hydroxamic acids has been reduced to an experimentally simple one-pot operation that addresses the issue of polyacylation without resorting to a large excess of hydroxylamine or to protection. Scope and selectivity were satisfactory with a wide range of substrates, including α,β-unsaturated acids and hydroxyacids.
Lingua originale | Inglese |
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pagine (da-a) | 5113-5115 |
Numero di pagine | 3 |
Rivista | Tetrahedron Letters |
Volume | 46 |
Numero di pubblicazione | 31 |
DOI | |
Stato di pubblicazione | Pubblicato - 1 ago 2005 |