Algorithms for warping of 2-D PAGE maps

MARCELLO MANFREDI; Elisa ROBOTTI; Emilio MARENGO

doi:10.1007/978-1-4939-3255-9_8

Algorithms for warping of 2-D PAGE maps

MARCELLO MANFREDI, Elisa ROBOTTI, Emilio MARENGO

Risultato della ricerca: Capitolo in libro/report/atti di convegno › Contributo in volume (Capitolo o Saggio)

Abstract

Software-based image analysis of 2-D PAGE maps is an important step for the investigation of proteome. Warping algorithms, which are employed to register spots among gels, are able to overcome the difficulties due to the low reproducibility of this analytical technique. Over the years, the research of new matching and warping mathematical methods has allowed the development of several routine applications of easy-to-use software. This chapter describes common and basic spatial transformations used for the alignment of protein spots present in different gel maps; some recently new approaches are also presented.

Lingua originale	Inglese
Titolo della pubblicazione ospite	Methods in Molecular Biology: 2D-PAGE map analysis
Editore	Springer New York
Pagine	119-154
Numero di pagine	36
Volume	1384
ISBN (stampa)	978-1-4939-3254-2
DOI	https://doi.org/10.1007/978-1-4939-3255-9_8
Stato di pubblicazione	Pubblicato - 2016

Keywords

2-D PAGE analysis
Data analysis
Gel matching
Image processing
Warping

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10.1007/978-1-4939-3255-9_8

http://hdl.handle.net/11579/73392

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abstract = "Software-based image analysis of 2-D PAGE maps is an important step for the investigation of proteome. Warping algorithms, which are employed to register spots among gels, are able to overcome the difficulties due to the low reproducibility of this analytical technique. Over the years, the research of new matching and warping mathematical methods has allowed the development of several routine applications of easy-to-use software. This chapter describes common and basic spatial transformations used for the alignment of protein spots present in different gel maps; some recently new approaches are also presented.",

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author = "MARCELLO MANFREDI and Elisa ROBOTTI and Emilio MARENGO",

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Algorithms for warping of 2-D PAGE maps

Abstract

Keywords

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