Acitretin-induced acral hemorrhagic lesions in Darier-White disease

Elisa Zavattaro; Celasco Melissa; Delrosso Giorgio; Ferri Simona; Bornacina Carlo; Valente Guido; Veronese Federica; Fusco Nicola; Gariglio Marisa; Colombo Enrico

Acitretin-induced acral hemorrhagic lesions in Darier-White disease

Elisa Zavattaro, Celasco Melissa, Delrosso Giorgio, Ferri Simona, Bornacina Carlo, Valente Guido, Veronese Federica, Fusco Nicola, Gariglio Marisa, Colombo Enrico

Dipartimento di Scienze della Salute

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

Darier-White disease (DD) is an autosomal-dominant inherited disease characterized by keratotic papules that are usually located in seborrheic areas. Systemic retinoids generally are first-line treatment in cases of diffuse DD. We report the case of an 84-year-old woman with a hypertrophic variant of DD with acral lesions. Oral retinoids (acitretin) were administered as a first treatment of DD, with good clinical results. After a few months, hemorrhagic vesicles developed on palmoplantar surfaces. Suspension of the therapy led to the disappearance of the cutaneous manifestations.

Lingua originale	Inglese
pagine (da-a)	E1-E5
Rivista	Cutis
Volume	94
Numero di pubblicazione	6
Stato di pubblicazione	Pubblicato - 2014

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title = "Acitretin-induced acral hemorrhagic lesions in Darier-White disease",

abstract = "Darier-White disease (DD) is an autosomal-dominant inherited disease characterized by keratotic papules that are usually located in seborrheic areas. Systemic retinoids generally are first-line treatment in cases of diffuse DD. We report the case of an 84-year-old woman with a hypertrophic variant of DD with acral lesions. Oral retinoids (acitretin) were administered as a first treatment of DD, with good clinical results. After a few months, hemorrhagic vesicles developed on palmoplantar surfaces. Suspension of the therapy led to the disappearance of the cutaneous manifestations.",

author = "Elisa Zavattaro and Celasco Melissa and Delrosso Giorgio and Ferri Simona and Bornacina Carlo and Valente Guido and Veronese Federica and Fusco Nicola and Gariglio Marisa and Colombo Enrico",

note = "Publisher Copyright: Copyright Cutis 2014.",

year = "2014",

language = "English",

volume = "94",

pages = "E1--E5",

journal = "Cutis",

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TY - JOUR

T1 - Acitretin-induced acral hemorrhagic lesions in Darier-White disease

AU - Zavattaro, Elisa

AU - Melissa, Celasco

AU - Giorgio, Delrosso

AU - Simona, Ferri

AU - Carlo, Bornacina

AU - Guido, Valente

AU - Federica, Veronese

AU - Nicola, Fusco

AU - Marisa, Gariglio

AU - Enrico, Colombo

PY - 2014

Y1 - 2014

N2 - Darier-White disease (DD) is an autosomal-dominant inherited disease characterized by keratotic papules that are usually located in seborrheic areas. Systemic retinoids generally are first-line treatment in cases of diffuse DD. We report the case of an 84-year-old woman with a hypertrophic variant of DD with acral lesions. Oral retinoids (acitretin) were administered as a first treatment of DD, with good clinical results. After a few months, hemorrhagic vesicles developed on palmoplantar surfaces. Suspension of the therapy led to the disappearance of the cutaneous manifestations.

AB - Darier-White disease (DD) is an autosomal-dominant inherited disease characterized by keratotic papules that are usually located in seborrheic areas. Systemic retinoids generally are first-line treatment in cases of diffuse DD. We report the case of an 84-year-old woman with a hypertrophic variant of DD with acral lesions. Oral retinoids (acitretin) were administered as a first treatment of DD, with good clinical results. After a few months, hemorrhagic vesicles developed on palmoplantar surfaces. Suspension of the therapy led to the disappearance of the cutaneous manifestations.

UR - http://www.scopus.com/inward/record.url?scp=84922127623&partnerID=8YFLogxK

M3 - Article

SN - 0011-4162

VL - 94

SP - E1-E5

JO - Cutis

JF - Cutis

IS - 6

ER -

Acitretin-induced acral hemorrhagic lesions in Darier-White disease

Abstract

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