A three-component synthesis of (1,3-oxazol-2-yl)-1,2-dihydro(iso)quinoline and its further structural diversifications

Gian Cesare Tron; Jieping Zhu

doi:10.1055/s-2005-862357

A three-component synthesis of (1,3-oxazol-2-yl)-1,2-dihydro(iso)quinoline and its further structural diversifications

Gian Cesare Tron, Jieping Zhu

Dipartimento di Scienze del Farmaco

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

A Reissert-type three-component synthesis of 1,3-oxazol-2-yl-1,2- dihydro(iso)quinoline is developed using α-isocyano β-phenyl propionamide as an isonitrile input. The structure of this multicomponent adduct is further diversified taking advantage of the rich chemistry of oxazole.

Lingua originale	Inglese
pagine (da-a)	532-534
Numero di pagine	3
Rivista	Synlett
Numero di pubblicazione	3
DOI	https://doi.org/10.1055/s-2005-862357
Stato di pubblicazione	Pubblicato - 16 feb 2005

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10.1055/s-2005-862357

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title = "A three-component synthesis of (1,3-oxazol-2-yl)-1,2-dihydro(iso)quinoline and its further structural diversifications",

abstract = "A Reissert-type three-component synthesis of 1,3-oxazol-2-yl-1,2- dihydro(iso)quinoline is developed using α-isocyano β-phenyl propionamide as an isonitrile input. The structure of this multicomponent adduct is further diversified taking advantage of the rich chemistry of oxazole.",

keywords = "Aminooxazole, Isocyanide, Isonitrile, Isoquinoline, Multicomponent reaction, Reissert reaction, Ugi reaction",

author = "Tron, \{Gian Cesare\} and Jieping Zhu",

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AU - Zhu, Jieping

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N2 - A Reissert-type three-component synthesis of 1,3-oxazol-2-yl-1,2- dihydro(iso)quinoline is developed using α-isocyano β-phenyl propionamide as an isonitrile input. The structure of this multicomponent adduct is further diversified taking advantage of the rich chemistry of oxazole.

AB - A Reissert-type three-component synthesis of 1,3-oxazol-2-yl-1,2- dihydro(iso)quinoline is developed using α-isocyano β-phenyl propionamide as an isonitrile input. The structure of this multicomponent adduct is further diversified taking advantage of the rich chemistry of oxazole.

KW - Aminooxazole

KW - Isocyanide

KW - Isonitrile

KW - Isoquinoline

KW - Multicomponent reaction

KW - Reissert reaction

KW - Ugi reaction

UR - https://www.scopus.com/pages/publications/14644439828

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DO - 10.1055/s-2005-862357

M3 - Article

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ER -

A three-component synthesis of (1,3-oxazol-2-yl)-1,2-dihydro(iso)quinoline and its further structural diversifications

Abstract

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