A randomized trial of cefepime and ceftazidime for the treatment of community-acquired pneumonia

P Bonfitto; V Lamorgese; Vietro T De; Mario MALERBA; L Rizzello; S Scoditti; R. Zuin

doi:10.1179/joc.1999.11.4.273

A randomized trial of cefepime and ceftazidime for the treatment of community-acquired pneumonia

P Bonfitto, V Lamorgese, Vietro T De, Mario MALERBA, L Rizzello, S Scoditti, R. Zuin

Dipartimento di Medicina Traslazionale

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

We compared the effectiveness and safety of ceftazidime and cefepime in hospitalized patients with community-acquired pneumonia. The 148 enrolled patients received 2 g ceftazidime three times daily or 2 g cefepime twice daily. The clinical success rate was the same for both drugs. Even the microbiological effectiveness was similar. Both drug regimens were well tolerated. We conclude that 2 g ceftazidime three times daily were as effective as 2 g cefepime twice daily for the treatment of community-acquired pneumonia in hospitalized patients. The cost of ceftazidime treatment was, however, higher than the cost of cefepime treatment.

Lingua originale	Inglese
pagine (da-a)	273-277
Numero di pagine	5
Rivista	Journal of Chemotherapy
Volume	11
Numero di pubblicazione	4
DOI	https://doi.org/10.1179/joc.1999.11.4.273
Stato di pubblicazione	Pubblicato - 1999

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10.1179/joc.1999.11.4.273

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abstract = "We compared the effectiveness and safety of ceftazidime and cefepime in hospitalized patients with community-acquired pneumonia. The 148 enrolled patients received 2 g ceftazidime three times daily or 2 g cefepime twice daily. The clinical success rate was the same for both drugs. Even the microbiological effectiveness was similar. Both drug regimens were well tolerated. We conclude that 2 g ceftazidime three times daily were as effective as 2 g cefepime twice daily for the treatment of community-acquired pneumonia in hospitalized patients. The cost of ceftazidime treatment was, however, higher than the cost of cefepime treatment.",

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T1 - A randomized trial of cefepime and ceftazidime for the treatment of community-acquired pneumonia

AU - Bonfitto, P

AU - Lamorgese, V

AU - De, Vietro T

AU - MALERBA, Mario

AU - Rizzello, L

AU - Scoditti, S

AU - Zuin, R.

PY - 1999

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N2 - We compared the effectiveness and safety of ceftazidime and cefepime in hospitalized patients with community-acquired pneumonia. The 148 enrolled patients received 2 g ceftazidime three times daily or 2 g cefepime twice daily. The clinical success rate was the same for both drugs. Even the microbiological effectiveness was similar. Both drug regimens were well tolerated. We conclude that 2 g ceftazidime three times daily were as effective as 2 g cefepime twice daily for the treatment of community-acquired pneumonia in hospitalized patients. The cost of ceftazidime treatment was, however, higher than the cost of cefepime treatment.

AB - We compared the effectiveness and safety of ceftazidime and cefepime in hospitalized patients with community-acquired pneumonia. The 148 enrolled patients received 2 g ceftazidime three times daily or 2 g cefepime twice daily. The clinical success rate was the same for both drugs. Even the microbiological effectiveness was similar. Both drug regimens were well tolerated. We conclude that 2 g ceftazidime three times daily were as effective as 2 g cefepime twice daily for the treatment of community-acquired pneumonia in hospitalized patients. The cost of ceftazidime treatment was, however, higher than the cost of cefepime treatment.

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JO - Journal of Chemotherapy

JF - Journal of Chemotherapy

IS - 4

ER -

A randomized trial of cefepime and ceftazidime for the treatment of community-acquired pneumonia

Abstract

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