A randomized trial of cefepime and ceftazidime for the treatment of community-acquired pneumonia

Piergiuseppe Bonfitto; V. Lamorgese; T. De Vietro; M. Malerba; L. Rizzello; S. Scoditti; R. Zuin

doi:10.1179/joc.1999.11.4.273

A randomized trial of cefepime and ceftazidime for the treatment of community-acquired pneumonia

Piergiuseppe Bonfitto, V. Lamorgese, T. De Vietro, M. Malerba, L. Rizzello, S. Scoditti, R. Zuin

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

We compared the effectiveness and safety of ceftazidime and cefepime in hospitalized patients with community-acquired pneumonia. The 148 enrolled patients received 2 g ceftazidime three times daily or 2 g cefepime twice daily. The clinical success rate was the same for both drugs. Even the microbiological effectiveness was similar. Both drug regimens were well tolerated. We conclude that 2 g ceftazidime three times daily were as effective as 2 g cefepime twice daily for the treatment of community-acquired pneumonia in hospitalized patients. The cost of ceftazidime treatment was, however, higher than the cost of cefepime treatment.

Lingua originale	Inglese
pagine (da-a)	273-277
Numero di pagine	5
Rivista	Journal of Chemotherapy
Volume	11
Numero di pubblicazione	4
DOI	https://doi.org/10.1179/joc.1999.11.4.273
Stato di pubblicazione	Pubblicato - 1999
Pubblicato esternamente	Sì

OSS delle Nazioni Unite

Questo processo contribuisce al raggiungimento dei seguenti obiettivi di sviluppo sostenibile

Accesso al documento

10.1179/joc.1999.11.4.273

Altri file e collegamenti

Link to publication in Scopus

Cita questo

@article{8f457f23f60843629261d2fe0058943f,

title = "A randomized trial of cefepime and ceftazidime for the treatment of community-acquired pneumonia",

abstract = "We compared the effectiveness and safety of ceftazidime and cefepime in hospitalized patients with community-acquired pneumonia. The 148 enrolled patients received 2 g ceftazidime three times daily or 2 g cefepime twice daily. The clinical success rate was the same for both drugs. Even the microbiological effectiveness was similar. Both drug regimens were well tolerated. We conclude that 2 g ceftazidime three times daily were as effective as 2 g cefepime twice daily for the treatment of community-acquired pneumonia in hospitalized patients. The cost of ceftazidime treatment was, however, higher than the cost of cefepime treatment.",

keywords = "Cefepime, Ceftazidime, Community-acquired pneumonia (CAP), Lower respiratory tract infection, Pneumonia, Randomized trial",

author = "Piergiuseppe Bonfitto and V. Lamorgese and {De Vietro}, T. and M. Malerba and L. Rizzello and S. Scoditti and R. Zuin",

year = "1999",

doi = "10.1179/joc.1999.11.4.273",

language = "English",

volume = "11",

pages = "273--277",

journal = "Journal of Chemotherapy",

issn = "1120-009X",

publisher = "Maney Publishing",

number = "4",

}

TY - JOUR

T1 - A randomized trial of cefepime and ceftazidime for the treatment of community-acquired pneumonia

AU - Bonfitto, Piergiuseppe

AU - Lamorgese, V.

AU - De Vietro, T.

AU - Malerba, M.

AU - Rizzello, L.

AU - Scoditti, S.

AU - Zuin, R.

PY - 1999

Y1 - 1999

N2 - We compared the effectiveness and safety of ceftazidime and cefepime in hospitalized patients with community-acquired pneumonia. The 148 enrolled patients received 2 g ceftazidime three times daily or 2 g cefepime twice daily. The clinical success rate was the same for both drugs. Even the microbiological effectiveness was similar. Both drug regimens were well tolerated. We conclude that 2 g ceftazidime three times daily were as effective as 2 g cefepime twice daily for the treatment of community-acquired pneumonia in hospitalized patients. The cost of ceftazidime treatment was, however, higher than the cost of cefepime treatment.

AB - We compared the effectiveness and safety of ceftazidime and cefepime in hospitalized patients with community-acquired pneumonia. The 148 enrolled patients received 2 g ceftazidime three times daily or 2 g cefepime twice daily. The clinical success rate was the same for both drugs. Even the microbiological effectiveness was similar. Both drug regimens were well tolerated. We conclude that 2 g ceftazidime three times daily were as effective as 2 g cefepime twice daily for the treatment of community-acquired pneumonia in hospitalized patients. The cost of ceftazidime treatment was, however, higher than the cost of cefepime treatment.

KW - Cefepime

KW - Ceftazidime

KW - Community-acquired pneumonia (CAP)

KW - Lower respiratory tract infection

KW - Pneumonia

KW - Randomized trial

UR - http://www.scopus.com/inward/record.url?scp=0032791881&partnerID=8YFLogxK

U2 - 10.1179/joc.1999.11.4.273

DO - 10.1179/joc.1999.11.4.273

M3 - Article

SN - 1120-009X

VL - 11

SP - 273

EP - 277

JO - Journal of Chemotherapy

JF - Journal of Chemotherapy

IS - 4

ER -

A randomized trial of cefepime and ceftazidime for the treatment of community-acquired pneumonia

Abstract

OSS delle Nazioni Unite

Accesso al documento

Altri file e collegamenti

Fingerprint

Cita questo