@article{b4af8a00d7024369a3de990b9b7042fc,
title = "A prenylbisabolane with NF-κB inhibiting properties from Cascarilla (Croton eluteria)",
abstract = "Investigation of the bark of Croton eluteria Bennett for biologically active compounds has led to the isolation of the new prenylbisabolane 3, whose structure was assessed by spectroscopic methods. The corresponding known enone 4 and the eudesmane sesquiterpene 2 were also obtained. Compound 3 proved active in selectively inhibiting the induction of NF-κB by tumor necrosis factor-α in T cells.",
keywords = "Cascarilla, Diterpenoids, NF-κB inhibition, Prenylbisabolane",
author = "Claudio Campagnuolo and Ernesto Fattorusso and Francesca Petrucci and Orazio Taglialatela-Scafati and Giovanni Appendino and Nieves Marquez and Eduardo Mu{\~n}oz",
note = "Funding Information: This work was supported by MIUR (Progetto Sostanze Naturali ed Analoghi Sintetici ad Attivit{\`a} Antitumorale). Mass and NMR spectra were recorded at the “Centro di Ricerca Interdipartimentale di Analisi Strumentale” of the University of Naples {\textquoteleft}Federico II{\textquoteright}. The assistance of the staff is gratefully acknowledged. E.M. was supported by the Spanish MCyT grant SAF2001-0037-C04-02.",
year = "2005",
month = jul,
day = "1",
doi = "10.1016/j.bmc.2005.04.025",
language = "English",
volume = "13",
pages = "4238--4242",
journal = "Bioorganic and Medicinal Chemistry",
issn = "0968-0896",
publisher = "Elsevier Ltd.",
number = "13",
}