A novel humanized mouse model with significant improvement of class-switched, antigen-specific antibody production

Keyphrases

• Human interleukin-6 100%
• Antigen-specific Antibody 100%
• Antibody Production 100%
• Humanized Mouse Model 100%
• Ovalbumin 60%
• Knock-in Mouse Model 40%
• Immunization 40%
• Specific Antibodies 40%
• B Cells 20%
• T Cells 20%
• Human Fetus 20%
• T Cell Differentiation 20%
• Somatic mutation 20%
• Adaptive Immunity 20%
• Mouse Strain 20%
• Adaptive Immune Response 20%
• Humanized Mice 20%
• B Cell Differentiation 20%
• Immune Function 20%
• Human Immune System 20%
• Fetal Liver 20%
• Cell Engraftment 20%
• Interleukin-6 Gene 20%
• B Cell Activation 20%
• Serum Immunoglobulin G 20%
• Human Hematopoiesis 20%
• Fetal Thymus 20%
• Thymopoiesis 20%
• B Cell Selection 20%
• Robust Adaptive 20%
• Class-switched Memory B Cells 20%
• Complex Surgery 20%

Immunology and Microbiology

• Interleukin 6 100%
• Mouse Model 100%
• Humanized Mouse 100%
• Antibody Generation 100%
• T Cell 40%
• B Cell 40%
• Adaptive Immune System 40%
• Cytokine 20%
• Thymus 20%
• Cell Differentiation 20%
• Somatic Mutation 20%
• Mouse Strain 20%
• Antibody Response 20%
• Engraftment 20%
• Hematopoiesis 20%
• Memory B Cell 20%
• Cell Selection 20%
• Immunoglobulin G 20%
• B Cell Activation 20%
• Immunoglobulin Blood Level 20%