A novel α-isocyanoacetamide-based three-component reaction for the synthesis of dialkyl 2-acyl-5-aminofuran-3,4-dicarboxylates

Riccardo Mossetti; Diego Caprioglio; Giampiero Colombano; Gian Cesare Tron; Tracey Pirali

doi:10.1039/c0ob00979b

A novel α-isocyanoacetamide-based three-component reaction for the synthesis of dialkyl 2-acyl-5-aminofuran-3,4-dicarboxylates

Riccardo Mossetti, Diego Caprioglio, Giampiero Colombano, Gian Cesare Tron, Tracey Pirali

Dipartimento di Scienze del Farmaco

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

α-Isocyanoacetamides, acyl chlorides and dialkylacetylenedicarboxylates undergo a smooth multicomponent reaction to produce dialkyl 2-acyl-5-aminofuran-3,4-dicarboxylates in good yield. The scope and mechanism of this new multicomponent transformation are discussed.

Lingua originale	Inglese
pagine (da-a)	1627-1631
Numero di pagine	5
Rivista	Organic and Biomolecular Chemistry
Volume	9
Numero di pubblicazione	5
DOI	https://doi.org/10.1039/c0ob00979b
Stato di pubblicazione	Pubblicato - 1 mar 2011

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10.1039/c0ob00979b

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title = "A novel α-isocyanoacetamide-based three-component reaction for the synthesis of dialkyl 2-acyl-5-aminofuran-3,4-dicarboxylates",

abstract = "α-Isocyanoacetamides, acyl chlorides and dialkylacetylenedicarboxylates undergo a smooth multicomponent reaction to produce dialkyl 2-acyl-5-aminofuran-3,4-dicarboxylates in good yield. The scope and mechanism of this new multicomponent transformation are discussed.",

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AU - Colombano, Giampiero

AU - Tron, Gian Cesare

AU - Pirali, Tracey

PY - 2011/3/1

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AB - α-Isocyanoacetamides, acyl chlorides and dialkylacetylenedicarboxylates undergo a smooth multicomponent reaction to produce dialkyl 2-acyl-5-aminofuran-3,4-dicarboxylates in good yield. The scope and mechanism of this new multicomponent transformation are discussed.

UR - https://www.scopus.com/pages/publications/79951614105

U2 - 10.1039/c0ob00979b

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A novel α-isocyanoacetamide-based three-component reaction for the synthesis of dialkyl 2-acyl-5-aminofuran-3,4-dicarboxylates

Abstract

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