A new ursane-type triterpenoid and other constituents from the leaves of Crataegus azarolus var. aronia

Sarbast A. Mahmud; Omar A.M. Al-Habib; Serena Bugoni; Marco Clericuzio; Giovanni Vidari

doi:10.1177/1934578x1601101103

A new ursane-type triterpenoid and other constituents from the leaves of Crataegus azarolus var. aronia

Sarbast A. Mahmud
, Omar A.M. Al-Habib
, Serena Bugoni
, Marco Clericuzio
, Giovanni Vidari

Dipartimento di Scienze e Innovazione Tecnologica

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

A new ursane-type triterpene acid, named azarolic acid (1), along with four known phenolic compounds and four known triterpene acids, was isolated from the crude EtOAc extract of the leaves of Crataegus azarolus var. aronia L. The structure of 1 was determined from 1D and 2D NMR spectroscopic data. Euscaphic acid showed high anti-vasoconstriction effects on aortic rings, supporting the use of this medicinal plant in cardiovascular disease.

Lingua originale	Inglese
pagine (da-a)	1637-1639
Numero di pagine	3
Rivista	Natural Product Communications
Volume	11
Numero di pubblicazione	11
DOI	https://doi.org/10.1177/1934578x1601101103
Stato di pubblicazione	Pubblicato - nov 2016

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title = "A new ursane-type triterpenoid and other constituents from the leaves of Crataegus azarolus var. aronia",

abstract = "A new ursane-type triterpene acid, named azarolic acid (1), along with four known phenolic compounds and four known triterpene acids, was isolated from the crude EtOAc extract of the leaves of Crataegus azarolus var. aronia L. The structure of 1 was determined from 1D and 2D NMR spectroscopic data. Euscaphic acid showed high anti-vasoconstriction effects on aortic rings, supporting the use of this medicinal plant in cardiovascular disease.",

keywords = "Aorta anti-contraction effects, Azarolic acid, Crataegus azarolus, Pentacyclic triterpenes, Rosaceae",

author = "Mahmud, \{Sarbast A.\} and Al-Habib, \{Omar A.M.\} and Serena Bugoni and Marco Clericuzio and Giovanni Vidari",

year = "2016",

month = nov,

doi = "10.1177/1934578x1601101103",

language = "English",

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AU - Bugoni, Serena

AU - Clericuzio, Marco

AU - Vidari, Giovanni

PY - 2016/11

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AB - A new ursane-type triterpene acid, named azarolic acid (1), along with four known phenolic compounds and four known triterpene acids, was isolated from the crude EtOAc extract of the leaves of Crataegus azarolus var. aronia L. The structure of 1 was determined from 1D and 2D NMR spectroscopic data. Euscaphic acid showed high anti-vasoconstriction effects on aortic rings, supporting the use of this medicinal plant in cardiovascular disease.

KW - Aorta anti-contraction effects

KW - Azarolic acid

KW - Crataegus azarolus

KW - Pentacyclic triterpenes

KW - Rosaceae

UR - https://www.scopus.com/pages/publications/85019094427

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JF - Natural Product Communications

IS - 11

ER -

A new ursane-type triterpenoid and other constituents from the leaves of Crataegus azarolus var. aronia

Abstract

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